Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | ACE | P12821 | 3/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | APAF1 | O14727 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.63 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.63 |
| ▸ | ITGAL | P20701 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.62 |
| ▸ | ECE1 | P42892 | 3/20 | 0.61 |
| ▸ | FPR2 | P25090 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MPO | P05164 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3451205 | 1.00 | ALOX15 (0.67) | ALOX15ACEKDM4EMAPTAPAF1 | |
| Acetic Acid SCHEMBL28587208 | 0.96 | ALOX15 (0.67) | ALOX15ACEKDM4EMAPTAPAF1 | |
| SCHEMBL3851355 | 0.90 | MEN1 (0.66) | ALOX15ACEKDM4EMAPTAPAF1 | |
| SCHEMBL30523242 | 0.89 | ALOX15 (0.54) | ALOX15ACEKDM4EMAPTAPAF1 | |
| SCHEMBL12313626 | 0.89 | ALOX15 (0.60) | ALOX15ACEKDM4EMAPTAPAF1 | |
| SCHEMBL17641895 | 0.89 | ALOX15 (0.60) | ALOX15ACEKDM4EMAPTAPAF1 | |
| SCHEMBL14374802 | 0.88 | ALOX15 (0.56) | ALOX15ACEKDM4EMAPTAPAF1 | |
| SCHEMBL9115508 | 0.88 | ALOX15 (0.65) | ALOX15ACEKDM4EMAPTAPAF1 | |
| SCHEMBL8710928 | 0.88 | SMN1; SMN2 (0.68) | ALOX15ACEKDM4EMAPTAPAF1 | |
| SCHEMBL22654181 | 0.88 | ALOX15 (0.65) | ALOX15ACEKDM4EMAPTAPAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568670-A1 | SIGMAR1 LIGAND FOR THE TREATMENT OF PANCREATIC CANCER | Institut National de la Santé et de la Recherche Médicale (FR) | 2025-06-18 | — | — | EP | disclosed |
| CN-116874515-B | Amino acid-BSH targeted hybrid compound, and preparation method and application thereof | 重庆高硼生物科技有限公司 | 2025-03-14 | — | — | CN | disclosed |
| CN-119470406-A | Phthalic dicarboxaldehyde disinfectant concentration detection test paper and preparation method thereof | 山东新华莎罗雅生物技术有限公司 | 2025-02-18 | — | — | CN | disclosed |
| WO-2024044271-A2 | METAL CHELATOR COMPOUNDS, COORDINATION COMPLEXES, AND METHODS OF PREPARATION AND USE THEREOF | UNIVERSITY OF PUERTO RICO (US) | 2024-02-29 | — | — | WO | disclosed |
| WO-2024033399-A1 | SIGMAR1 LIGAND FOR THE TREATMENT OF PANCREATIC CANCER | Institut National de la Santé et de la Recherche Médicale (FR) | 2024-02-15 | — | — | WO | disclosed |
| WO-2024033400-A1 | SK2 INHIBITOR FOR THE TREATMENT OF PANCREATIC CANCER | Institut National de la Santé et de la Recherche Médicale (FR) | 2024-02-15 | — | — | WO | disclosed |
| EP-4308241-A1 | COMBINATION THERAPY FOR CANCER | IO Biotech ApS (DK) | 2024-01-24 | — | — | EP | disclosed |
| CN-117396071-A | Delivery particles with high core to wall ratio | 恩盖普有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-116874515-A | Amino acid-BSH targeted hybrid compound, and preparation method and application thereof | 重庆高硼生物科技有限公司 | 2023-10-13 | — | — | CN | disclosed |
| CN-113336768-B | Multi-target tyrosine kinase inhibitor | 深圳海王医药科技研究院有限公司 | 2022-08-19 | — | — | CN | disclosed |
| US-5616684-A | CYCLIC HEXAPEPTIDE CONTAINING ASPARTIC ACID AND DERIVATIVES, 2-THIENYLGLYCINE, LEUCINE, AND TRYPTOPHAN; ENDOTHELIN RECEPTOR ANTAGONIST | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0714909-A1 | Composition for prophylaxis or treatment of pulmonary circulatory diseases | Takeda Chemical Industries, Ltd. (JP) | 1996-06-05 | — | — | EP | disclosed |
| CN-1109780-A | Sustained-release preparation of anti-endothelin substance | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-10-11 | — | — | CN | disclosed |
| EP-0662143-A1 | MICROORGANISMS FOR THE PRODUCTION OF TRYPTOPHAN AND PROCESS FOR PRODUCING THE SAME. | CONSORTIUM ELEKTROCHEM IND (DE) | 1995-07-12 | — | — | EP | disclosed |
| EP-0647449-A1 | Sustained-release preparation of anti-endothelin substance | Takeda Chemical Industries, Ltd. (JP) | 1995-04-12 | — | — | EP | disclosed |
| EP-0626174-A2 | Methods and compositions for the prophylactic and/or therapeutic treatment of organ hypofunction | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-11-30 | — | — | EP | disclosed |
| WO-1994008031-A1 | MICROORGANISMS FOR THE PRODUCTION OF TRYPTOPHAN AND PROCESS FOR PRODUCING THE SAME | Consortium für elektrochemische Industrie GmbH (DE) | 1994-04-14 | — | — | WO | disclosed |
| EP-0552417-A1 | Cyclic peptides and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-07-28 | — | — | EP | disclosed |
| EP-0528312-A2 | Cyclic peptides and use thereof | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |
| EP-0124502-A2 | Conjugates of vinblastine and its derivatives, process for their preparation and pharmaceutical compositions containing these conjugates | OMNICHEM Société anonyme (BE) | 1984-11-07 | — | — | EP | disclosed |