SCHEMBL345151

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23809253	0.85	KDM4E (0.54)	KDM4EL3MBTL1KDM4AEGLN1KDM6B
	SCHEMBL69673	0.77	KDM4E (0.77)	KDM4EL3MBTL1KDM4AEGLN1KDM6B
	SCHEMBL26551421	0.77	KDM4E (0.62)	KDM4EL3MBTL1KDM4AEGLN1KDM6B
	SCHEMBL12847483	0.76	CYP2C19 (0.43)	KDM4EL3MBTL1ALDH1A1RAB9ANPC1
	SCHEMBL30503371	0.74	SLC6A2 (0.59)	KDM4EL3MBTL1KDM4AEGLN1KDM6B
	SCHEMBL11803761	0.74	SLC6A2 (0.59)	KDM4EL3MBTL1KDM4AEGLN1KDM6B
	SCHEMBL23809130	0.74	KDM4E (0.50)	KDM4EL3MBTL1KDM4AEGLN1KDM6B
	SCHEMBL2586914	0.73	KDM4E (0.50)	KDM4EL3MBTL1KDM4AEGLN1KDM6B
	SCHEMBL24908450	0.73	KDM4E (0.49)	KDM4EL3MBTL1ALDH1A1TDP1SELPLG
	SCHEMBL27575501	0.73	SLC6A2 (0.57)	KDM4EL3MBTL1KDM4AEGLN1KDM6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.