Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.37 |
| ▸ | MMP13 | P45452 | 2/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.37 |
| ▸ | MMP1 | P03956 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3451562 | 1.00 | MCHR1 (0.44) | MCHR1CA12CA2CA9PLA2G2C | |
| SCHEMBL3629469 | 1.00 | MCHR1 (0.44) | MCHR1CA12CA2CA9PLA2G2C | |
| SCHEMBL10773783 | 0.97 | MCHR1 (0.47) | MCHR1CA12CA2CA9PLA2G2C | |
| SCHEMBL5902719 | 0.97 | MCHR1 (0.47) | MCHR1CA12CA2CA9PLA2G2C | |
| SCHEMBL25613650 | 0.97 | MCHR1 (0.47) | MCHR1CA12CA2CA9PLA2G2C | |
| SCHEMBL31648088 | 0.97 | MCHR1 (0.47) | MCHR1CA12CA2CA9PLA2G2C | |
| SCHEMBL3086955 | 0.97 | MCHR1 (0.47) | MCHR1CA12CA2CA9PLA2G2C | |
| SCHEMBL15272323 | 0.97 | MCHR1 (0.47) | MCHR1CA12CA2CA9PLA2G2C | |
| SCHEMBL2374757 | 0.97 | MCHR1 (0.47) | MCHR1CA12CA2CA9PLA2G2C | |
| SCHEMBL29051969 | 0.91 | MCHR1 (0.44) | MCHR1CA12CA2CA9PLA2G2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273916-B2 | Crystal comprising (2R)-2-propyloctanoic acid and amine | ONO PHARMACEUTICAL CO., LTD. (JP) | 2012-09-25 | — | — | US | disclosed |
| US-20100331414-A1 | CRYSTAL COMPRISING (2R)-2-PROPYLOCTANOIC ACID AND AMINE | ONO PHARMACEUTICAL CO., LTD (JP) | 2010-12-30 | — | — | US | disclosed |
| US-7820715-B2 | Crystal comprising (2R)-2-propyloctanoic acid and amine | ONO PHARMACEUTICAL CO., LTD. (JP) | 2010-10-26 | — | — | US | disclosed |
| US-7589221-B2 | Industrial scale process; treats neurodegenerative diseases; high optical purity; less dangerous reaction | ONO PHARMACEUTICAL CO., LTD. (JP) | 2009-09-15 | — | — | US | disclosed |
| US-20080090907-A1 | Crystal Comprising (2R)-2-Propyloctanoic Acid and Amine | ONO PHARMACEUTICAL CO., LTD. (JP) | 2008-04-17 | — | — | US | disclosed |
| EP-1741697-A1 | CRYSTAL COMPRISING (2R)-2-PROPYLOCTOIC ACID AND AMINE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-01-10 | — | — | EP | disclosed |
| US-20060135802-A1 | Process for producing (2r)-2-propyloctanoic acid and intermediate therefor | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090907-A1 | Crystal Comprising (2R)-2-Propyloctanoic Acid and Amine | TAS2R5, FFAR2, HRH2 | MCHR1 1900/4885CA12 3475/4885CA2 2842/4885 |
| US-20060135802-A1 | Process for producing (2r)-2-propyloctanoic acid and intermediate therefor | CYP51A1, POR, GRHPR | MCHR1 1785/4885CA12 1420/4885CA2 723/4885 |
| US-20100331414-A1 | CRYSTAL COMPRISING (2R)-2-PROPYLOCTANOIC ACID AND AMINE | FFAR2, CYP3A5, DECR2 | MCHR1 1225/4885CA12 2843/4885CA2 2652/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.