SCHEMBL3451612

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3918977	0.91	KMT2A (0.48)	KMT2AMEN1L3MBTL1GSTO1CPB1
	SCHEMBL1744940	0.88	KMT2A (0.53)	KMT2AMEN1L3MBTL1GSTO1CPB1
	SCHEMBL3917014	0.87	KMT2A (0.45)	KMT2AMEN1L3MBTL1GSTO1CPB1
	SCHEMBL3915895	0.87	CYP1A2 (0.45)	KMT2AMEN1L3MBTL1GSTO1CPB1
	SCHEMBL1744722	0.85	KMT2A (0.55)	KMT2AMEN1L3MBTL1GSTO1CPB1
	SCHEMBL3622785	0.85	KMT2A (0.53)	KMT2AMEN1L3MBTL1GSTO1CPB1
	SCHEMBL3451487	0.82	KMT2A (0.54)	KMT2AMEN1L3MBTL1GSTO1CPB1
	SCHEMBL18674595	0.81	KMT2A (0.51)	KMT2AMEN1L3MBTL1GSTO1CPB1
	SCHEMBL3912223	0.80	PPARD (0.57)	KMT2AMEN1NPSR1MAPT
	SCHEMBL1746662	0.80	KMT2A (0.57)	KMT2AMEN1L3MBTL1GSTO1CPB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.