Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | PDE1A | P54750 | 1/20 | 0.49 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.49 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29537275 | 1.00 | MAPT (0.49) | MAPTALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL31359722 | 0.88 | KMT2A (0.57) | MAPTALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL1396090 | 0.88 | KMT2A (0.57) | MAPTALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL4864061 | 0.86 | HTT (0.60) | MAPTALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL10876406 | 0.85 | GOT1 (0.75) | MAPTALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL1268020 | 0.84 | ESR1 (0.49) | MAPTALDH1A1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL27938933 | 0.84 | KDR (0.45) | MAPTALDH1A1SMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL7904780 | 0.84 | ALDH1A1 (0.60) | MAPTALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL10662227 | 0.83 | SMN1; SMN2 (0.58) | MAPTALDH1A1SMN1; SMN2KDM4EHPGD | |
| SCHEMBL8551380 | 0.82 | LMNA (0.45) | MAPTALDH1A1SMN1; SMN2KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57048972-A | — | — | None | — | — | JP | disclosed |
| JP-10109936-A | — | — | None | — | — | JP | disclosed |
| JP-56053659-A | — | — | None | — | — | JP | disclosed |
| CN-115160378-B | Red-light organic electrophosphorescent material and preparation method and application thereof | 安徽工业大学 | 2024-08-20 | — | — | CN | disclosed |
| CN-115010765-B | Red-light organic electrophosphorescent material and preparation method and application thereof | 安徽工业大学 | 2024-08-20 | — | — | CN | disclosed |
| US-20230303570-A1 | KINASE INHIBITORS AND USES THEREOF | ABM THERAPEUTICS CORP (US) | 2023-09-28 | — | — | US | disclosed |
| US-20230303570-A1 | KINASE INHIBITORS AND USES THEREOF | ABM THERAPEUTICS CORP (US) | 2023-09-28 | — | — | US | disclosed |
| CN-116710453-A | Kinase inhibitors and uses thereof | 璧辰医药技术股份有限公司 | 2023-09-05 | — | — | CN | disclosed |
| EP-4192582-A1 | KINASE INHIBITORS AND USES THEREOF | ABM Therapeutics Corporation (US) | 2023-06-14 | — | — | EP | disclosed |
| CN-115160378-A | Red light organic electrophosphorescent material and preparation method and application thereof | 安徽工业大学 | 2022-10-11 | — | — | CN | disclosed |
| JP-H10109936-A | AGENT FOR TREATING AND PREVENTING DIABETIC NEUROPATHY | MITSUBISHI CHEM CORP | 1998-04-28 | — | — | JP | disclosed |
| EP-0825187-A1 | Condensed pyridazinyl guanidines, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-02-25 | — | — | EP | disclosed |
| US-5643911-A | CEREBROVASCULAR DISEASE | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-07-01 | — | — | US | disclosed |
| US-5462941-A | 1-(cyclohexylalkylamino)-4-(phenyl, thienyl, or furyl) phthalazines; anti-platelet agglutination agents for treatment or prevention of cerebro- or cardiovascular disorders | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0449203-B1 | 4-Phenylphthalazine derivatives | MITSUBISHI CHEM IND (JP) | 1994-12-07 | — | — | EP | disclosed |
| EP-0534443-A1 | 3,6-Disubstituted pyridazine derivatives | Mitsubishi Chemical Corporation (JP) | 1993-03-31 | — | — | EP | disclosed |
| US-5089494-A | 4-PHENYLPHTHALAZINE DERIVATIVES WHICH INHIBIT PLATELET AGGREGATION | MITSUBISHI KASEI CORPORATION (JP) | 1992-02-18 | — | — | US | disclosed |
| EP-0449203-A1 | 4-Phenylphthalazine derivatives | Mitsubishi Chemical Corporation (JP) | 1991-10-02 | — | — | EP | disclosed |
| JP-S5748972-A | 4-PHENYLPHTHALAZINE DERIVATIVE | MITSUBISHI YUKA YAKUHIN KK | 1982-03-20 | — | — | JP | disclosed |
| JP-S5653659-A | BLOOD PLATELET COAGULATION SUPPRESSING AGENT | MITSUBISHI YUKA YAKUHIN KK | 1981-05-13 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230303570-A1 | KINASE INHIBITORS AND USES THEREOF | ERBB2, ERBB3, ERBB4 | MAPT 2358/4885ALDH1A1 1859/4885SMN1; SMN2 2432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.