Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 15/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13109714 | 0.99 | MRGPRX4 (0.45) | MRGPRX4NR4A2SMN1; SMN2TP53PKM | |
| SCHEMBL3452584 | 0.92 | ALOX5 (0.47) | NR4A2SMN1; SMN2RXFP1KDM4ECYP1A2 | |
| SCHEMBL3452202 | 0.92 | KDM4E (0.40) | MRGPRX4NR4A2SMN1; SMN2RXFP1KDM4E | |
| SCHEMBL13109717 | 0.91 | ALOX5 (0.48) | NR4A2SMN1; SMN2RXFP1KDM4ECYP1A2 | |
| SCHEMBL3453187 | 0.89 | CYP1A2 (0.41) | NR4A2SMN1; SMN2RXFP1RAB9AKDM4E | |
| SCHEMBL13109711 | 0.88 | CYP1A2 (0.41) | NR4A2SMN1; SMN2RXFP1RAB9AKDM4E | |
| SCHEMBL3452582 | 0.85 | MMP13 (0.41) | NR4A2SMN1; SMN2RXFP1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL3453153 | 0.83 | MRGPRX4 (0.43) | MRGPRX4SMN1; SMN2TP53RAB9ACYP1A2 | |
| SCHEMBL3453185 | 0.82 | TRPM8 (0.41) | NR4A2SMN1; SMN2RXFP1RAB9AKDM4E | |
| SCHEMBL13109685 | 0.75 | CYP1A2 (0.43) | SMN1; SMN2TP53RXFP1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820704-B2 | Substituted heteroaryl derivatives, compositions, and methods of use | TRANSTECH PHARMA, INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-20050261294-A1 | Substituted heteroaryl derivatives, compositions, and methods of use | VTVX HOLDINGS I LLC | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261294-A1 | Substituted heteroaryl derivatives, compositions, and methods of use | MC5R, MC3R, MC4R | MRGPRX4 185/4885NR4A2 652/4885SMN1; SMN2 3982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.