Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 6/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.31 |
| ▸ | GRK6 | P43250 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL244232 | 0.98 | CNR2 (0.35) | CNR2KMT2ALMNATP53ATM | |
| SCHEMBL4936634 | 0.83 | KMT2A (0.39) | CNR2KMT2ALMNATP53ATM | |
| SCHEMBL13086215 | 0.79 | CNR2 (0.41) | CNR2KMT2AALDH1A1MEN1HSP90AA1 | |
| SCHEMBL4443205 | 0.79 | CYP2D6 (0.44) | CNR2KMT2ALMNATP53ALDH1A1 | |
| SCHEMBL9347243 | 0.79 | LTA4H (0.38) | CNR2KMT2ALMNASMN1; SMN2NPSR1 | |
| SCHEMBL25082006 | 0.75 | MAPK1 (0.41) | KMT2ASMN1; SMN2ALDH1A1MEN1CYP2C9 | |
| SCHEMBL16749608 | 0.75 | CYP19A1 (0.43) | — | |
| SCHEMBL25081942 | 0.75 | MAPK1 (0.41) | KMT2ASMN1; SMN2ALDH1A1MEN1CYP2C9 | |
| SCHEMBL4434764 | 0.74 | MAPT (0.45) | KMT2AATMALDH1A1MEN1L3MBTL1 | |
| SCHEMBL9644373 | 0.74 | ALDH1A1 (0.41) | CNR2KMT2ALMNASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820404-B2 | Protein cleavage method and use thereof | ARKRAY, INC. (JP) | 2010-10-26 | — | — | US | disclosed |
| US-20090081718-A1 | Protein cleavage method and thereof | ARKRAY, INC. (JP) | 2009-03-26 | — | — | US | disclosed |