Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3453716 | 0.78 | ALDH1A1 (0.36) | ALDH1A1CYP2D6CA12CA1CA2 | |
| SCHEMBL3453217 | 0.74 | ALDH1A1 (0.41) | ALDH1A1CYP2D6 | |
| SCHEMBL13110750 | 0.72 | ALDH1A1 (0.39) | ALDH1A1CYP2D6 | |
| SCHEMBL264829 | 0.72 | — | — | |
| SCHEMBL3452906 | 0.71 | ALDH1A1 (0.39) | ALDH1A1CYP2D6 | |
| SCHEMBL31694248 | 0.70 | ALDH1A1 (0.42) | ALDH1A1CYP2D6CA12CA1CA2 | |
| SCHEMBL264731 | 0.68 | ALDH1A1 (0.41) | ALDH1A1CYP2D6CA12CA1CA2 | |
| SCHEMBL17993848 | 0.68 | PRSS1 (0.36) | ALDH1A1CYP2D6 | |
| SCHEMBL31694205 | 0.67 | ALDH1A1 (0.39) | ALDH1A1CYP2D6CA12CA1CA2 | |
| SCHEMBL31694204 | 0.67 | ALDH1A1 (0.39) | ALDH1A1CYP2D6CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539688-B1 | NOVEL COMPOUNDS COMPRISING A THIOCARBONYL-SULFANYL GROUP, WHICH CAN BE USED FOR THE RADICAL SYNTHESIS OF ALPHA-PERFLUOROALKYLAMINES | CENTRE NAT RECH SCIENT (FR) | 2016-08-10 | — | — | EP | disclosed |
| US-7820831-B2 | Compounds comprising a thiocarbonyl-sulfanyl group which can be used for the radical synthesis of α-perfluoroalkylamine compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2010-10-26 | — | — | US | disclosed |
| US-7820831-B2 | Compounds comprising a thiocarbonyl-sulfanyl group which can be used for the radical synthesis of α-perfluoroalkylamine compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2010-10-26 | — | — | US | disclosed |
| US-7820831-B2 | Compounds comprising a thiocarbonyl-sulfanyl group which can be used for the radical synthesis of α-perfluoroalkylamine compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2010-10-26 | — | — | US | disclosed |
| US-20080306281-A1 | NOVEL COMPOUNDS COMPRISING A THIOCARBONYL-SULFANYL GROUP WHICH CAN BE USED FOR THE RADICAL SYNTHESIS OF ALPHA-PERFLUOROALKYLAMINE COMPOUNDS | RHODIA OPERATIONS (FR) | 2008-12-11 | — | — | US | disclosed |
| US-20080306281-A1 | NOVEL COMPOUNDS COMPRISING A THIOCARBONYL-SULFANYL GROUP WHICH CAN BE USED FOR THE RADICAL SYNTHESIS OF ALPHA-PERFLUOROALKYLAMINE COMPOUNDS | RHODIA OPERATIONS (FR) | 2008-12-11 | — | — | US | disclosed |
| US-20080306281-A1 | NOVEL COMPOUNDS COMPRISING A THIOCARBONYL-SULFANYL GROUP WHICH CAN BE USED FOR THE RADICAL SYNTHESIS OF ALPHA-PERFLUOROALKYLAMINE COMPOUNDS | RHODIA OPERATIONS (FR) | 2008-12-11 | — | — | US | disclosed |
| US-7423161-B2 | Compounds comprising a thiocarbonyl-sulfanyl group, which can be used for the radical synthesis of-α-perfluoroalkylamines | RHODIA CHIMIE (FR) | 2008-09-09 | — | — | US | disclosed |
| US-7423161-B2 | Compounds comprising a thiocarbonyl-sulfanyl group, which can be used for the radical synthesis of-α-perfluoroalkylamines | RHODIA CHIMIE (FR) | 2008-09-09 | — | — | US | disclosed |
| US-7423161-B2 | Compounds comprising a thiocarbonyl-sulfanyl group, which can be used for the radical synthesis of-α-perfluoroalkylamines | RHODIA CHIMIE (FR) | 2008-09-09 | — | — | US | disclosed |
| US-20060122404-A1 | Novel compounds comprising a thiocarbonyl-sulfanyl group, which can be used for the radical synthesis of-alpha-perfluoroalkylamines | RHODIA CHIMIE (FR) | 2006-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122404-A1 | Novel compounds comprising a thiocarbonyl-sulfanyl group, which can be used for the radical synthesis of-alpha-perfluoroalkylamines | PFAS, CYP2F1, SULT1A1 | ALDH1A1 367/4885CYP2D6 185/4885CA12 2725/4885 |
| US-20080306281-A1 | NOVEL COMPOUNDS COMPRISING A THIOCARBONYL-SULFANYL GROUP WHICH CAN BE USED FOR THE RADICAL SYNTHESIS OF ALPHA-PERFLUOROALKYLAMINE COMPOUNDS | PFAS, SULT1A1, CYP2F1 | ALDH1A1 344/4885CYP2D6 215/4885CA12 2997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.