Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | THPO | P40225 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3453126 | 0.85 | PLA2G2C (0.35) | ALDH1A1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL801237 | 0.84 | ALDH1A1 (0.34) | ALDH1A1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL801063 | 0.84 | ALDH1A1 (0.34) | ALDH1A1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL14157901 | 0.74 | TRPV1 (0.46) | TRPV1ALDH1A1KDM4EMAPTTHRB | |
| SCHEMBL17722836 | 0.73 | ALDH1A1 (0.37) | TRPV1ALDH1A1KDM4EMAPTTHRB | |
| SCHEMBL17777044 | 0.73 | ALDH1A1 (0.37) | TRPV1ALDH1A1KDM4EMAPTTHRB | |
| SCHEMBL17777043 | 0.73 | ALDH1A1 (0.37) | TRPV1ALDH1A1KDM4EMAPTTHRB | |
| SCHEMBL801285 | 0.73 | ALDH1A1 (0.33) | ALDH1A1KDM4EMAPTTHRBALOX15 | |
| SCHEMBL228531 | 0.72 | — | — | |
| SCHEMBL20228901 | 0.70 | TRPV1 (0.39) | TRPV1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539688-B1 | NOVEL COMPOUNDS COMPRISING A THIOCARBONYL-SULFANYL GROUP, WHICH CAN BE USED FOR THE RADICAL SYNTHESIS OF ALPHA-PERFLUOROALKYLAMINES | CENTRE NAT RECH SCIENT (FR) | 2016-08-10 | — | — | EP | disclosed |
| US-7820831-B2 | Compounds comprising a thiocarbonyl-sulfanyl group which can be used for the radical synthesis of α-perfluoroalkylamine compounds | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2010-10-26 | — | — | US | disclosed |
| US-20080306281-A1 | NOVEL COMPOUNDS COMPRISING A THIOCARBONYL-SULFANYL GROUP WHICH CAN BE USED FOR THE RADICAL SYNTHESIS OF ALPHA-PERFLUOROALKYLAMINE COMPOUNDS | RHODIA OPERATIONS (FR) | 2008-12-11 | — | — | US | disclosed |
| US-7423161-B2 | Compounds comprising a thiocarbonyl-sulfanyl group, which can be used for the radical synthesis of-α-perfluoroalkylamines | RHODIA CHIMIE (FR) | 2008-09-09 | — | — | US | disclosed |
| US-20060122404-A1 | Novel compounds comprising a thiocarbonyl-sulfanyl group, which can be used for the radical synthesis of-alpha-perfluoroalkylamines | RHODIA CHIMIE (FR) | 2006-06-08 | — | — | US | disclosed |
| EP-1539688-A2 | NOVEL COMPOUNDS COMPRISING A THIOCARBONYL-SULFANYL GROUP, WHICH CAN BE USED FOR THE RADICAL SYNTHESIS OF ALPHA-PERFLUOROALKYLAMINES | Rhodia Chimie (FR) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004024681-A2 | NOVEL COMPOUNDS COMPRISING A THIOCARBONYL-SULFANYL GROUP, WHICH CAN BE USED FOR THE RADICAL SYNTHESIS OF ALPHA-PERFLUOROALKYLAMINES | RHODIA CHIMIE (FR) | 2004-03-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122404-A1 | Novel compounds comprising a thiocarbonyl-sulfanyl group, which can be used for the radical synthesis of-alpha-perfluoroalkylamines | PFAS, CYP2F1, SULT1A1 | TRPV1 4094/4885ALDH1A1 367/4885KDM4E 2583/4885 |
| US-20080306281-A1 | NOVEL COMPOUNDS COMPRISING A THIOCARBONYL-SULFANYL GROUP WHICH CAN BE USED FOR THE RADICAL SYNTHESIS OF ALPHA-PERFLUOROALKYLAMINE COMPOUNDS | PFAS, SULT1A1, CYP2F1 | TRPV1 4233/4885ALDH1A1 344/4885KDM4E 3189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.