Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR7 | P34969 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | HTR2C | P28335 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR5A | P47898 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL10773004 | 0.97 | ALDH1A1 (0.50) | ALDH1A1HTR1AHTR7SIGMAR1TSHR | |
| Tannin Pyrogallol SCHEMBL29026000 | 0.95 | ALDH1A1 (0.47) | ALDH1A1HTR1AHTR7SIGMAR1TSHR | |
| Biphenyl SCHEMBL29176815 | 0.95 | ALDH1A1 (0.47) | ALDH1A1HTR1AHTR7SIGMAR1TSHR | |
| Biphenyl SCHEMBL28051011 | 0.91 | ALDH1A1 (0.56) | ALDH1A1HTR1AHTR7SIGMAR1TSHR | |
| Biphenyl SCHEMBL27720670 | 0.91 | ALDH1A1 (0.64) | ALDH1A1HTR1AHTR7SIGMAR1TSHR | |
| Piperidine SCHEMBL28705840 | 0.88 | HTR1A (0.53) | ALDH1A1HTR1AHTR7TSHRUSP2 | |
| Biphenyl SCHEMBL8201983 | 0.88 | ALDH1A1 (0.60) | ALDH1A1HTR1AHTR7SIGMAR1TSHR | |
| Piperidine SCHEMBL29221182 | 0.87 | ALDH1A1 (0.45) | ALDH1A1HTR1AHTR7SIGMAR1HTR2C | |
| Biphenyl SCHEMBL27760037 | 0.85 | ALDH1A1 (0.56) | ALDH1A1HTR1AHTR7SIGMAR1TSHR | |
| Piperidine SCHEMBL28984946 | 0.85 | HTR1A (0.52) | ALDH1A1HTR1AHTR7SIGMAR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117327000-A | Biphenyl tetrahydropyrrole compound and preparation method and application thereof | 海南因瑞生物医药科技有限公司 | 2024-01-02 | — | — | CN | claimed |
| WO-2009054855-A9 | OLIGOSILOXANE MODIFIED LIQUID CRYSTAL FORMULATIONS AND DEVICES USING SAME | DOW CORNING CORPORATION (US) | 2010-10-07 | — | — | WO | claimed |
| WO-2008126106-A2 | NOVEL AND IMPROVED PROCESSES FOR THE PREPARATION OF INTERMEDIATES OF DARIFENACIN, DARIFENACIN AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | SATYANARAYANA REDDY MANNE (IN) | 2008-10-23 | — | — | WO | claimed |
| CN-117327000-A | Biphenyl tetrahydropyrrole compound and preparation method and application thereof | 海南因瑞生物医药科技有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-117327000-A | Biphenyl tetrahydropyrrole compound and preparation method and application thereof | 海南因瑞生物医药科技有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-117327000-A | Biphenyl tetrahydropyrrole compound and preparation method and application thereof | 海南因瑞生物医药科技有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-102264695-A | Haloalkyl containing compounds as cysteine protease inhibitors | — | 2011-11-30 | — | — | CN | disclosed |
| WO-2008126106-A2 | NOVEL AND IMPROVED PROCESSES FOR THE PREPARATION OF INTERMEDIATES OF DARIFENACIN, DARIFENACIN AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS | SATYANARAYANA REDDY MANNE (IN) | 2008-10-23 | — | — | WO | disclosed |