SCHEMBL3453786

SCHEMBL3453786

CCCCCCCCCCCCc1ccc2c(oc3ccccc32)c1CCCCCCCCCCCC

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.40
LIPG Q9Y5X9 1/20 0.40
SRC P12931 1/20 0.39
MAPT P10636 1/20 0.39
PTGS2 P35354 1/20 0.38
HSD17B10 Q99714 2/20 0.38
TYR P14679 1/20 0.38
NPC1 O15118 2/20 0.38
RAB9A P51151 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
KDM4E B2RXH2 1/20 0.37
ALDH1A1 P00352 1/20 0.37
HPGD P15428 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5013814 1.00 ESR1 (0.40) ESR1LIPGSRCMAPTPTGS2
SCHEMBL21436950 0.84 ALOX5 (0.47) ESR1LIPGMAPTPTGS2KDM4E
SCHEMBL21436921 0.84 ALOX5 (0.47) ESR1LIPGMAPTPTGS2KDM4E
SCHEMBL21436947 0.84 ALOX5 (0.47) ESR1LIPGMAPTPTGS2KDM4E
SCHEMBL11994184 0.82 ALOX5 (0.48) LIPGMAPTPTGS2NPC1RAB9A
SCHEMBL16981606 0.82 NPC1 (0.42) LIPGSRCMAPTNPC1RAB9A
SCHEMBL5010801 0.80 SRC (0.42) SRCMAPTHSD17B10TYRKDM4E
SCHEMBL28686355 0.79 ESR1 (0.39) ESR1LIPGMAPTPTGS2HSD17B10
SCHEMBL28445314 0.77 MAPT (0.40) ESR1SRCMAPTHSD17B10NPC1
SCHEMBL16985150 0.75 MAPT (0.43) LIPGMAPTNPC1RAB9AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7820747-B2 Method for preparing adhesives from stable butadiene polymer latexes LORD CORPORATION (US) 2010-10-26 US disclosed
EP-1049742-B1 AQUEOUS PRIMER OR COATING LORD CORP (US) 2008-03-26 EP disclosed
US-20080045644-A1 METHOD FOR PREPARING ADHESIVES FROM STABLE BUTADIENE POLYMER LATEXES LORD CORPORATION 2008-02-21 US disclosed
US-20070243372-A1 AQUEOUS ADHESIVE LORD CORPORATION 2007-10-18 US disclosed
US-20070244247-A1 AQUEOUS ADHESIVE FOR RUBBER TO METAL BONDING LORD CORPORATION 2007-10-18 US disclosed
EP-1049748-B1 AQUEOUS METAL TREATMENT COMPOSITION LORD CORP (US) 2007-01-10 EP disclosed
US-7109265-B2 Autodepositable adhesive LORD CORPORATION (US) 2006-09-19 US disclosed
US-20060172076-A1 Autodeposition metal dip coating process LORD CORPORATION 2006-08-03 US disclosed
US-7037385-B2 Aqueous metal treatment composition LORD CORPORATION (US) 2006-05-02 US disclosed
US-20050252782-A9 Autodeposition metal dip coating process LORD CORPORATION 2005-11-17 US disclosed
US-6383307-B1 INCLUDES AN AQUEOUS DISPERSION OF A PHENOLIC NOVOLAK RESIN THAT INCLUDES WATER AND A REACTION PRODUCT OF A PHENOLIC RESIN PRECURSOR, A MODIFYING AGENT CONTAINING A FUNCTIONAL GROUP, AND AN IONIC GORUP; A MULTIHYDROXY PHENOLIC COMPOUND AND A AN LORD CORPORATION 2002-05-07 US disclosed
US-20020023694-A1 AQUEOUS METAL TREATMENT COMPOSITION LORD CORPORATION 2002-02-28 US disclosed
EP-1144535-A2 AUTODEPOSITABLE ADHESIVE Lord Corporation (US) 2001-10-17 EP disclosed
EP-1049729-A1 BUTADIENE POLYMER LATEX Lord Corporation (US) 2000-11-08 EP disclosed
EP-1049742-A1 AQUEOUS PRIMER OR COATING Lord Corporation (US) 2000-11-08 EP disclosed
EP-1049748-A1 AQUEOUS METAL TREATMENT COMPOSITION Lord Corporation (US) 2000-11-08 EP disclosed
WO-2000043131-A2 AUTODEPOSITABLE ADHESIVE LORD CORPORATION (US) 2000-07-27 WO disclosed
WO-1999037713-A1 AQUEOUS PRIMER OR COATING LORD CORPORATION (US) 1999-07-29 WO disclosed
WO-1999037722-A1 AQUEOUS METAL TREATMENT COMPOSITION LORD CORPORATION (US) 1999-07-29 WO disclosed
WO-1999037697-A1 BUTADIENE POLYMER LATEX LORD CORPORATION (US) 1999-07-29 WO disclosed