SCHEMBL5010801

SCHEMBL5010801

CCCCCCCCCCCCCCCCCCc1ccc2c(oc3cc(Br)c(Br)cc32)c1CCCCCCCCCCCCCCCCCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 3/20 0.42
STS P08842 1/20 0.37
TYR P14679 2/20 0.36
MAPT P10636 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
TP53 P04637 1/20 0.36
CYP3A4 P08684 1/20 0.36
ALOX5 P09917 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
HTT P42858 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 2/20 0.36
GAA P10253 2/20 0.36
ERAP1 Q9NZ08 1/20 0.36
SIRT2 Q8IXJ6 1/20 0.34
PPARG P37231 1/20 0.34
KDM4E B2RXH2 1/20 0.34
GLA P06280 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5013814 0.80 ESR1 (0.40) SRCTYRMAPTALDH1A1KDM4E
SCHEMBL3453786 0.80 ESR1 (0.40) SRCTYRMAPTALDH1A1KDM4E
SCHEMBL5010158 0.75 SRC (0.35) SRCSTSTYRMAPTMEN1
SCHEMBL16806162 0.72 LIPG (0.42) SRCMAPTALOX5PPARG
SCHEMBL16807711 0.71 SRC (0.39) SRCSTSTYRMAPTMEN1
SCHEMBL28460292 0.71 ALOX5 (0.47) TYRMAPTMEN1KMT2ATP53
SCHEMBL28453738 0.71 ALOX5 (0.47) TYRMAPTMEN1KMT2ATP53
SCHEMBL17637378 0.70 TYR (0.49) SRCSTSTYRMAPTMEN1
SCHEMBL17637442 0.70 TYR (0.49) SRCSTSTYRMAPTMEN1
SCHEMBL17637428 0.70 TYR (0.49) SRCSTSTYRMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080207864-A1 Organosilanes, Process For Production of the Same, and Use Thereof SHARP KABUSHIKI KAISHA (JP) 2008-08-28 US disclosed