Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3453786 | 1.00 | ESR1 (0.40) | ESR1LIPGSRCMAPTPTGS2 | |
| SCHEMBL21436950 | 0.84 | ALOX5 (0.47) | ESR1LIPGMAPTPTGS2KDM4E | |
| SCHEMBL21436921 | 0.84 | ALOX5 (0.47) | ESR1LIPGMAPTPTGS2KDM4E | |
| SCHEMBL21436947 | 0.84 | ALOX5 (0.47) | ESR1LIPGMAPTPTGS2KDM4E | |
| SCHEMBL11994184 | 0.82 | ALOX5 (0.48) | LIPGMAPTPTGS2NPC1RAB9A | |
| SCHEMBL16981606 | 0.82 | NPC1 (0.42) | LIPGSRCMAPTNPC1RAB9A | |
| SCHEMBL5010801 | 0.80 | SRC (0.42) | SRCMAPTHSD17B10TYRKDM4E | |
| SCHEMBL28686355 | 0.79 | ESR1 (0.39) | ESR1LIPGMAPTPTGS2HSD17B10 | |
| SCHEMBL28445314 | 0.77 | MAPT (0.40) | ESR1SRCMAPTHSD17B10NPC1 | |
| SCHEMBL16985150 | 0.75 | MAPT (0.43) | LIPGMAPTNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080207864-A1 | Organosilanes, Process For Production of the Same, and Use Thereof | SHARP KABUSHIKI KAISHA (JP) | 2008-08-28 | — | — | US | disclosed |