SCHEMBL345402

SCHEMBL345402

OC(O)COc1ccccc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.68
SCN4A P35499 2/20 0.54
CYP2D6 P10635 3/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
ADRB2 P07550 1/20 0.53
ADRB1 P08588 1/20 0.53
ADRB3 P13945 1/20 0.53
KDM4E B2RXH2 1/20 0.52
RECQL P46063 2/20 0.50
MAPT P10636 2/20 0.50
ALDH1A1 P00352 1/20 0.50
TSHR P16473 1/20 0.50
HIF1A Q16665 1/20 0.50
KCNA3 P22001 1/20 0.50
MAOA P21397 1/20 0.50
PTGS1 P23219 1/20 0.50
HTT P42858 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
MTNR1A P48039 3/20 0.48
MTNR1B P49286 3/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28556067 0.87 LMNA (0.50) LMNACYP2D6KDM4EMAPTALDH1A1
SCHEMBL484242 0.87 LMNA (0.50) LMNACYP2D6KDM4EMAPTALDH1A1
SCHEMBL9564637 0.85 LMNA (0.68) LMNASCN4ACYP2D6L3MBTL1ADRB2
SCHEMBL267463 0.85 LMNA (0.68) LMNASCN4ACYP2D6L3MBTL1ADRB2
SCHEMBL14880144 0.81 LMNA (0.63) LMNASCN4ACYP2D6L3MBTL1ADRB2
SCHEMBL3254859 0.81 LMNA (1.00) LMNASCN4ACYP2D6L3MBTL1ADRB2
SCHEMBL1618880 0.81 LMNA (1.00) LMNASCN4ACYP2D6L3MBTL1ADRB2
SCHEMBL17386434 0.81 LMNA (0.63) LMNASCN4ACYP2D6L3MBTL1ADRB2
SCHEMBL1369854 0.81 LMNA (0.63) LMNASCN4ACYP2D6L3MBTL1ADRB2
SCHEMBL2943775 0.81 LMNA (1.00) LMNASCN4ACYP2D6L3MBTL1ADRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 980 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11525074-B2 Two-component curing adhesive, laminated film, laminated film-manufacturing apparatus, and method for manufacturing laminated film DIC CORPORATION (JP) 2022-12-13 US claimed
EP-3798275-B1 CERAMIC INK AND USE THEREOF FOR DECORATING CERAMIC OBJECTS SMALTICERAM UNICER S P A (IT) 2022-07-13 EP claimed
EP-3798275-A1 CERAMIC INK AND USE THEREOF FOR DECORATING CERAMIC OBJECTS SMALTICERAM UNICER S.P.A. (IT) 2021-03-31 EP claimed
CN-111743846-A Isolation and protection emulsion and preparation method thereof 广州葆雀化妆品有限公司 2020-10-09 CN claimed
CN-110423326-A A kind of wastewaters with modified calcium sulfate whiskers/polyurethane composite foam material and its preparation process UNIV SHAANXI SCIENCE & TECH 2019-11-08 CN claimed
CN-110396162-A A kind of sealing Low temperature-resistanpolyurethane polyurethane formula and preparation process VONESEALS TECH SHANGHAI CO LTD 2019-11-01 CN claimed
CN-110387121-A Composite material, elastic element and isolation mounting and preparation method thereof 中国船舶重工集团公司第七一一研究所 2019-10-29 CN claimed
CN-109517131-A Thermoplastic silicone polyurethane and its synthetic method 万华化学集团股份有限公司 2019-03-26 CN claimed
CN-108794721-A Preparation method of polyurethane hollow microspheres 安徽大学 2018-11-13 CN claimed
CN-108314769-A A kind of reactive extrursion prepares the method and its application of polylactic acid based polyurethanes elastomer 中国科学院宁波材料技术与工程研究所 2018-07-24 CN claimed
CN-106589871-A Lignin modified PHA biodegradable plastic and preparing method thereof 济宁明升新材料有限公司 2017-04-26 CN claimed
CN-106280325-A A kind of polylactide type polyurethane polydactyl acid alloy and preparation method thereof 中国科学院宁波材料技术与工程研究所 2017-01-04 CN claimed
US-8445584-B2 Aqueous polyurethane resin MITSUI CHEMICALS, INC. (JP) 2013-05-21 US claimed
EP-1720578-A2 BACTERIOSTATIC ESTERS FOR TOPICAL USE Vama Farmacosmetica S.R.L. (IT) 2006-11-15 EP claimed
WO-2005079852-A2 BACTERIOSTATIC ESTERS FOR TOPICAL USE VAMA FARMCOSMETICA S.R.L. (IT) 2005-09-01 WO claimed
US-20050182124-A1 Ester bacteriostat for stabilizing cosmetics VAMA FARMACOSMETICA S.R.L. 2005-08-18 US claimed
US-5688890-A Thermoplastic polyurethane composition KURARAY CO., LTD. (JP) 1997-11-18 US claimed
EP-0385015-A1 Terpene-based solvents for washout of photopolymer printing plates W.R. Grace & Co.-Conn. (US) 1990-09-05 EP claimed
EP-0125466-B1 PROCESS FOR REPEATED REVERSE COATING WITH POLYURETHANE SOLUTIONS BAYER AG (DE) 1987-06-24 EP claimed
US-4294951-A Rapid curing polyurethane elastomer prepared from a diphenylmethanediisocyanate based liquid prepolymer and a curing agent containing a polytetramethylene ether glycol, a diol and an organometallic catalyst MITSUI-NISSO CORPORATION (JP) 1981-10-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050182124-A1 Ester bacteriostat for stabilizing cosmetics CUTA, PGA5, ACP3 LMNA 2837/4885SCN4A 4552/4885CYP2D6 2195/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.