Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454212 | 0.90 | SMN1; SMN2 (0.39) | KDM4EALDH1A1KMT2AMEN1RAB9A | |
| SCHEMBL3455595 | 0.83 | SCD (0.47) | ALDH1A1 | |
| SCHEMBL3454678 | 0.81 | ALDH1A1 (0.48) | LMNACDC7DBF4KDM4EALDH1A1 | |
| SCHEMBL3454521 | 0.81 | LMNA (0.51) | LMNACDC7DBF4KDM4EALDH1A1 | |
| SCHEMBL3455045 | 0.80 | SCD (0.57) | LMNAALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL3454424 | 0.79 | CDC7 (0.52) | LMNACDC7DBF4KDM4EALDH1A1 | |
| SCHEMBL3454105 | 0.78 | LMNA (0.44) | LMNACDC7DBF4KDM4EALDH1A1 | |
| SCHEMBL3454224 | 0.77 | LMNA (0.46) | LMNACDC7DBF4KDM4EALDH1A1 | |
| SCHEMBL3454216 | 0.75 | CDC7 (0.54) | LMNACDC7DBF4KDM4EALDH1A1 | |
| SCHEMBL3367577 | 0.73 | SCD (0.49) | ALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007143597-A9 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-11-11 | — | — | WO | disclosed |