Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 4/20 | 0.52 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454216 | 0.86 | CDC7 (0.54) | CDC7DBF4ALDH1A1KDM4ELMNA | |
| SCHEMBL3454854 | 0.86 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EHPGDSMN1; SMN2NPC1 | |
| SCHEMBL3454224 | 0.84 | LMNA (0.46) | CDC7DBF4ALDH1A1KDM4ELMNA | |
| SCHEMBL3454521 | 0.84 | LMNA (0.51) | CDC7DBF4ALDH1A1KDM4ELMNA | |
| SCHEMBL3454678 | 0.83 | ALDH1A1 (0.48) | CDC7DBF4ALDH1A1KDM4ELMNA | |
| SCHEMBL3454105 | 0.83 | LMNA (0.44) | CDC7DBF4ALDH1A1KDM4ELMNA | |
| SCHEMBL3454511 | 0.81 | CDC7 (0.52) | CDC7DBF4ALDH1A1KDM4ELMNA | |
| SCHEMBL3454078 | 0.79 | LMNA (0.41) | CDC7DBF4ALDH1A1KDM4ELMNA | |
| SCHEMBL3454229 | 0.78 | SCD (0.55) | HPGDNPC1 | |
| SCHEMBL10997300 | 0.75 | LMNA (0.60) | CDC7DBF4ALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007143597-A9 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-11-11 | — | — | WO | claimed |
| WO-2007143597-A9 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-11-11 | — | — | WO | disclosed |