Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454603 | 0.90 | RAB9A (0.51) | RAB9AMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL3454066 | 0.89 | PPARA (0.46) | SCDRAB9AMEN1KMT2AMAPT | |
| SCHEMBL3447237 | 0.86 | SCD (0.56) | SCDRAB9AMAPTALDH1A1PPARA | |
| SCHEMBL3454459 | 0.83 | SCD (0.55) | SCDMAPTPPARASMN1; SMN2LMNA | |
| SCHEMBL3447843 | 0.81 | RAB9A (0.48) | RAB9AMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL3454071 | 0.80 | RAB9A (0.47) | SCDRAB9AMEN1KMT2AMAPT | |
| SCHEMBL3455026 | 0.78 | PPARA (0.55) | KMT2AMAPTPPARASMN1; SMN2 | |
| SCHEMBL3455855 | 0.77 | PPARA (0.55) | SCDMAPTPPARAPOLBLMNA | |
| SCHEMBL3454120 | 0.77 | MAPT (0.47) | SCDRAB9AMAPTPPARANPC1 | |
| SCHEMBL3454346 | 0.76 | ALDH1A1 (0.50) | KMT2AALDH1A1NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | claimed |
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | disclosed |