Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 7/20 | 0.52 |
| ▸ | SCD | O00767 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454082 | 0.90 | SCD (0.50) | PPARASCDMAPTLMNATP53 | |
| SCHEMBL3454459 | 0.89 | SCD (0.55) | PPARASCDMAPTLMNATP53 | |
| SCHEMBL3455304 | 0.89 | PPARA (0.56) | PPARASCDCHRM4PPARDPPARG | |
| SCHEMBL3454415 | 0.88 | MAOB (0.43) | PPARASCDMAPTCHRM4PPARG | |
| SCHEMBL3448039 | 0.87 | SCD (0.44) | PPARASCDMAPTLMNACHRM4 | |
| SCHEMBL3454066 | 0.86 | PPARA (0.46) | PPARASCDMAPTLMNATP53 | |
| SCHEMBL3455070 | 0.86 | PPARA (0.43) | PPARASCDMAPTLMNATP53 | |
| SCHEMBL3455855 | 0.85 | PPARA (0.55) | PPARASCDMAPTLMNATP53 | |
| SCHEMBL3455839 | 0.84 | HTT (0.46) | LMNATP53HTT | |
| SCHEMBL3454081 | 0.83 | SCD (0.50) | SCDLMNACHRM4HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007482-A2 | THIAZOLE DERIVATIVES AS STEAROYL COA DESATURASE INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2010-01-21 | — | — | WO | disclosed |