SCHEMBL345451

SCHEMBL345451

C=C(C)C(=O)NCc1cc(-n2nc3ccccc3n2)c(O)c(C(C)(C)CCCCC)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 3/20 0.33
CNR2 P34972 3/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
POLB P06746 2/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
USP2 O75604 1/20 0.32
LMNA P02545 1/20 0.32
PKM P14618 1/20 0.32
HPGD P15428 1/20 0.32
ALOX15 P16050 1/20 0.32
TSHR P16473 1/20 0.32
ALOX12 P18054 1/20 0.32
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
GAA P10253 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ASAH1 Q13510 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL345788 0.85 NPC1 (0.33) CNR1CNR2NPC1RAB9APOLB
SCHEMBL345190 0.84 CNR2 (0.34) CNR1CNR2NPC1RAB9APOLB
SCHEMBL75758 0.81 KDM4E (0.38) CNR1CNR2NPC1RAB9APOLB
SCHEMBL74919 0.81 NPC1 (0.39) CNR1CNR2NPC1RAB9APOLB
SCHEMBL12803215 0.81 NPC1 (0.37) CNR1CNR2NPC1RAB9APOLB
SCHEMBL508930 0.80 NPC1 (0.34) CNR1CNR2NPC1RAB9APOLB
SCHEMBL28019476 0.79 THRA (0.37) CNR2NPC1RAB9APOLBASAH1
SCHEMBL9291284 0.79 HDAC3 (0.43) CNR1CNR2POLBSMN1; SMN2ALDH1A1
SCHEMBL345326 0.78 CNR2 (0.35) CNR1CNR2NPC1RAB9APOLB
SCHEMBL673359 0.77 CNR1 (0.40) CNR1CNR2NPC1RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2416381-A1 PROTECTIVE SHEET FOR SOLAR CELL MODULE AND SOLAR CELL MODULE LINTEC Corporation (JP) 2012-02-08 EP disclosed
US-20120012164-A1 PROTECTIVE SHEET FOR SOLAR CELL MODULE AND SOLAR CELL MODULE LINTEC CORPORATION (JP) 2012-01-19 US disclosed
US-8003222-B2 Resin composition for forming ultraviolet absorbing layer and laminate comprising ultraviolet absorbing layer NIPPON SHOKUBAI CO., LTD. (JP) 2011-08-23 US disclosed
US-20090110936-A1 Resin Composition for Forming Ultraviolet Absorbing Layer and Laminate Comprising Ultraviolet Absorbing Layer NIPPON SHOKUBAI CO., LTD. (JP) 2009-04-30 US disclosed
WO-2007037501-A9 RESIN COMPOSITION FOR FORMING ULTRAVIOLET ABSORBING LAYER AND LAMINATE COMPRISING ULTRAVIOLET ABSORBING LAYER NIPPON CATALYTIC CHEM IND (JP) 2007-05-24 WO disclosed