Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SCD | O00767 | 11/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3454982 | 0.89 | SCD (0.50) | KDM4EALDH1A1HPGDHSD17B10SCD | |
| SCHEMBL3455051 | 0.85 | SCD (0.46) | KDM4EALDH1A1HPGDHSD17B10SCD | |
| SCHEMBL3454345 | 0.83 | MMP13 (0.42) | KDM4EALDH1A1HPGDHSD17B10SCD | |
| SCHEMBL3454373 | 0.80 | LMNA (0.51) | KDM4EALDH1A1HPGDHSD17B10SCD | |
| SCHEMBL3454719 | 0.80 | LMNA (0.51) | KDM4EALDH1A1HPGDHSD17B10SCD | |
| SCHEMBL3454995 | 0.80 | SCD (0.58) | HPGDSCD | |
| SCHEMBL3454466 | 0.80 | SCD (0.51) | KDM4EALDH1A1HPGDHSD17B10SCD | |
| SCHEMBL3455053 | 0.78 | CCR1 (0.47) | SCDCCR1CHRM4 | |
| SCHEMBL3454788 | 0.78 | SENP5 (0.44) | SCDCCR1CHRM4 | |
| SCHEMBL3456455 | 0.77 | LMNA (0.47) | ALDH1A1HPGDSCDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007143597-A9 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-11-11 | — | — | WO | claimed |
| WO-2007143597-A9 | ORGANIC COMPOUNDS | NOVARTIS AG (CH) | 2010-11-11 | — | — | WO | disclosed |