SCHEMBL3455145

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3455309	0.83	ADORA2A (0.43)	ADORA2AADORA1ADORA2BADORA3PIK3R1
	SCHEMBL3455589	0.83	ADORA2A (0.55)	ADORA2AADORA1ADORA2BADORA3PIK3R1
	SCHEMBL3455974	0.81	ADORA2A (0.42)	ADORA2AADORA1ADORA2BADORA3PIK3R1
	SCHEMBL13942226	0.80	ADORA2A (0.49)	ADORA2AADORA1ADORA2BADORA3PIK3R1
	SCHEMBL5453909	0.79	DHFR (0.51)	ADORA2AADORA1ADORA2BADORA3PIK3R1
	Hydrochloric Acid SCHEMBL3455706	0.79	ADORA2A (0.48)	ADORA2AADORA1ADORA2BADORA3PIK3R1
	SCHEMBL7150942	0.79	ADORA2A (0.46)	ADORA2AADORA1ADORA2BADORA3TSHR
	SCHEMBL3455891	0.78	MAPT (0.41)	ADORA2AADORA1ADORA2BADORA3PIK3R1
	SCHEMBL3456020	0.77	ADORA2A (0.52)	ADORA2AADORA1ADORA2BADORA3PIK3R1
	SCHEMBL3455110	0.77	ADORA2A (0.58)	ADORA2AADORA1ADORA2BPIK3R1PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.