SCHEMBL345568

SCHEMBL345568

CC(=O)c1ccc(Br)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiophene SCHEMBL9373298 0.88 CES2 (0.53)
SCHEMBL2872059 0.82 GSK3B (0.67)
SCHEMBL1244072 0.80 CES2 (0.73)
SCHEMBL71972 0.78
SCHEMBL14624168 0.77 GSK3B (0.63)
SCHEMBL1476181 0.76
SCHEMBL1455897 0.76
SCHEMBL17028614 0.76
SCHEMBL24198806 0.76 CES2 (0.59)
SCHEMBL70702 0.76 DAO (0.63)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 768 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119409712-A Azafluoroboro fluorescent dye molecule with near infrared two-region absorption and preparation method and application thereof 泰州职业技术学院 2025-02-11 CN claimed
CN-114478500-B Coumarin two-photon initiator and synthesis method and application thereof 浙江大学 2024-03-29 CN claimed
CN-117486872-A Mechanical ball milling synthesis method of aminothiazole compound 浙江工业大学 2024-02-02 CN claimed
CN-113201295-A Release film with high residual adhesion rate and preparation method thereof 佛山华韩卫生材料有限公司 2021-08-03 CN claimed
CN-113185531-A Preparation method of photoinitiator for release film 佛山华韩卫生材料有限公司 2021-07-30 CN claimed
CN-111171040-A Dihydrofuropyran/pyridoindole derivatives and synthesis method thereof 常州大学 2020-05-19 CN claimed
CN-104693167-A Novel crystal form crystal of 1-(5-bromothiophene-2-yl)-3-(nitrobenzophenone)-2alkene-1-ketone and preparation method thereof UNIV TIANJIN 2015-06-10 CN claimed
US-6096124-A Ink compositions XEROX CORPORATION (US) 2000-08-01 US claimed
EP-4731216-A1 HETEROARYL-AMINE COMPOUNDS AND USE THEREOF AS HDAC6 INHIBITORS Augustine Therapeutics (BE) 2026-04-29 EP disclosed
US-12552757-B2 NRF2-activating compound SENJU PHARMACEUTICAL CO., LTD. (JP) 2026-02-17 US disclosed
US-20250382290-A1 SALTS OF SOS1 INHIBITORS Mirati Therapeutics, Inc. (US) 2025-12-18 US disclosed
EP-4650002-A1 ANILINE-BASED MODULATORS OF THE NUCLEAR RECEPTOR TLX (NR2E1) Ludwig-Maximilians-Universität (DE) 2025-11-19 EP disclosed
US-20250346585-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2025-11-13 US disclosed
US-20250270220-A1 SOS1 INHIBITORS Mirati Therapeutics, Inc. (US) 2025-08-28 US disclosed
EP-0087953-A2 Antibacterial 1-normon-2-yl-heterocyclic compounds BEECHAM GROUP PLC (GB) 1983-09-07 EP disclosed
US-4366321-A Preparation of 2-halo-3-nitro-5-acyl thiophenes and intermediate compounds EASTMAN KODAK COMPANY (US) 1982-12-28 US disclosed
US-4105663-A HYPOTENSIVE, BLOCKING AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1978-08-08 US disclosed
US-4093628-A HYPOTENSIVE AGENTS, BLOCKING AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1978-06-06 US disclosed
US-4082772-A HYPOTENSIVE AGENTS, B-ADRENERGIC BLOCKING AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1978-04-04 US disclosed
US-4024156-A Thiophene ethanolamines AMERICAN HOME PRODUCTS CORPORATION (US) 1977-05-17 US disclosed