Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 10/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3456480 | 0.88 | P2RX7 (0.77) | P2RX7TDP1L3MBTL1MEN1KMT2A | |
| SCHEMBL4207060 | 0.82 | P2RX7 (0.67) | P2RX7KMT2A | |
| SCHEMBL6940565 | 0.76 | P2RX7 (1.00) | P2RX7MEN1KMT2A | |
| SCHEMBL4207053 | 0.69 | P2RX7 (0.85) | P2RX7MEN1KMT2A | |
| SCHEMBL27826899 | 0.65 | P2RX7 (0.56) | P2RX7L3MBTL1 | |
| SCHEMBL11884308 | 0.61 | P2RX7 (1.00) | P2RX7MEN1KMT2A | |
| SCHEMBL6941699 | 0.61 | P2RX7 (0.70) | P2RX7MEN1KMT2A | |
| SCHEMBL6939890 | 0.61 | P2RX7 (0.70) | P2RX7MEN1KMT2A | |
| SCHEMBL9311985 | 0.61 | KMT2A (0.75) | P2RX7L3MBTL1MEN1KMT2A | |
| SCHEMBL1199010 | 0.61 | P2RX7 (0.66) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2239012-A2 | Pharmaceutical use of substituted amides | High Point Pharmaceuticals, LLC (US) | 2010-10-13 | — | — | EP | disclosed |