Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HNF4A | P41235 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL358654 | 0.85 | ALDH1A1 (0.43) | HDAC4HDAC2HDAC8HDAC6HNF4A | |
| SCHEMBL910660 | 0.83 | ALDH1A1 (0.44) | HDAC4HDAC2HDAC8HDAC6HNF4A | |
| Benzene SCHEMBL28163950 | 0.82 | ALDH1A1 (0.48) | HDAC4HDAC2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL29838597 | 0.82 | ALDH1A1 (0.48) | HDAC4HDAC2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL21933 | 0.82 | ALDH1A1 (0.48) | HDAC4HDAC2HDAC8HDAC6ALDH1A1 | |
| Methyl Alcohol SCHEMBL28631854 | 0.80 | ALDH1A1 (0.46) | HDAC4HDAC2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL28326904 | 0.80 | ALDH1A1 (0.46) | HDAC4HDAC2HDAC8HDAC6ALDH1A1 | |
| Water SCHEMBL29954878 | 0.80 | ALDH1A1 (0.46) | HDAC4HDAC2HDAC8HDAC6ALDH1A1 | |
| SCHEMBL60283 | 0.79 | HDAC4 (0.65) | HDAC4HDAC2HDAC8HDAC6HNF4A | |
| SCHEMBL30605196 | 0.79 | HDAC4 (0.65) | HDAC4HDAC2HDAC8HDAC6HNF4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111747995-B | Nitrogen-containing aryloxy cyclopentadienyl titanium compound and preparation method and application thereof | 上海化工研究院有限公司 | 2023-02-21 | — | — | CN | disclosed |
| CN-111747995-A | Nitrogen-containing aryloxy cyclopentadienyl titanium compound and preparation method and application thereof | 上海化工研究院有限公司 | 2020-10-09 | — | — | CN | disclosed |
| US-20150266892-A1 | AMPK Modulators | MERCURY THERAPEUTICS INC (US) | 2015-09-24 | — | — | US | disclosed |
| US-8980895-B2 | AMPK modulators | MERCURY THERAPEUTICS, INC. (US) | 2015-03-17 | — | — | US | disclosed |
| US-20120302576-A1 | AMPK MODULATORS | MERCURY THERAPEUTICS, INC. | 2012-11-29 | — | — | US | disclosed |
| US-8273744-B2 | AMPK modulators | MERCURY THERAPEUTICS, INC. (US) | 2012-09-25 | — | — | US | disclosed |
| EP-2240016-A1 | AMPK MODULATORS | Mercury Therapeutics, Inc. (US) | 2010-10-20 | — | — | EP | disclosed |
| US-20100009992-A1 | AMPK MODULATORS | MERCURY THERAPEUTICS, INC. | 2010-01-14 | — | — | US | disclosed |
| WO-2009100130-A1 | AMPK MODULATORS | MERCURY THERAPEUTICS, INC. (US) | 2009-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150266892-A1 | AMPK Modulators | PRKAG1, PRKAG2, PRKAG3 | HDAC4 405/4885HDAC2 817/4885HDAC8 680/4885 |
| US-20120302576-A1 | AMPK MODULATORS | PRKAG1, PRKAG2, PRKAG3 | HDAC4 405/4885HDAC2 817/4885HDAC8 680/4885 |
| US-20100009992-A1 | AMPK MODULATORS | PRKAG1, PRKAG2, PRKAG3 | HDAC4 405/4885HDAC2 817/4885HDAC8 680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.