Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | HBB | P68871 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6809164 | 0.84 | KDM4E (0.59) | KDM4EMAPTALDH1A1MAPK1HPGD | |
| SCHEMBL4905343 | 0.74 | KDM4E (0.44) | KDM4EMAPTALDH1A1MAPK1HPGD | |
| Acetic Acid SCHEMBL3457064 | 0.73 | KDM4E (0.82) | KDM4EMAPTALDH1A1MAPK1HPGD | |
| SCHEMBL27635351 | 0.69 | HTT (0.51) | KDM4EMAPTALDH1A1MAPK1HPGD | |
| Hydrogen Peroxide SCHEMBL6662236 | 0.69 | KDM4E (0.93) | KDM4EMAPTALDH1A1MAPK1HPGD | |
| SCHEMBL9519260 | 0.69 | CYP19A1 (0.51) | KDM4EMAPTALDH1A1MAPK1HSD17B10 | |
| SCHEMBL29357684 | 0.69 | MAPT (1.00) | KDM4EMAPTALDH1A1MAPK1HPGD | |
| SCHEMBL37700 | 0.69 | MAPT (1.00) | KDM4EMAPTALDH1A1MAPK1HPGD | |
| Succinamide SCHEMBL9208547 | 0.69 | KDM4E (0.78) | KDM4EMAPTALDH1A1MAPK1HPGD | |
| SCHEMBL15466849 | 0.68 | TP53 (0.47) | KDM4EMAPTALDH1A1MAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2260862-B1 | Compositions and methods for treating tumors presenting survivin antigens | MERCK PATENT GMBH (DE) | 2012-06-27 | — | — | EP | disclosed |
| EP-2260862-A1 | Compositions and methods for treating tumors presenting survivin antigens | Merck Patent GmbH (DE) | 2010-12-15 | — | — | EP | disclosed |
| EP-1931376-A2 | COMPOSITIONS AND METHODS FOR TREATING TUMORS PRESENTING SURVIVIN ANTIGENS | Merck Patent GmbH (DE) | 2008-06-18 | — | — | EP | disclosed |
| US-20070104689-A1 | Compositions and methods for treating tumors presenting survivin antigens | MERCK PATENT GMBH (DE) | 2007-05-10 | — | — | US | disclosed |
| WO-2007039192-A2 | COMPOSITIONS AND METHODS FOR TREATING TUMORS PRESENTING SURVIVIN ANTIGENS | MERCK PATENT GMBH (DE) | 2007-04-12 | — | — | WO | disclosed |