Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 3/20 | 0.59 |
| ▸ | HBB | P68871 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3457067 | 0.84 | KDM4E (0.51) | KDM4EALDH1A1MAPTHSD17B10MEN1 | |
| SCHEMBL37700 | 0.74 | MAPT (1.00) | KDM4EALDH1A1MAPTHSD17B10MEN1 | |
| SCHEMBL29357684 | 0.74 | MAPT (1.00) | KDM4EALDH1A1MAPTHSD17B10MEN1 | |
| SCHEMBL15466849 | 0.74 | TP53 (0.47) | KDM4EALDH1A1MAPTHSD17B10MEN1 | |
| Iodide SCHEMBL33722025 | 0.73 | MAPT (0.97) | KDM4EALDH1A1MAPTHSD17B10MEN1 | |
| Water SCHEMBL28844053 | 0.73 | MAPT (0.97) | KDM4EALDH1A1MAPTHSD17B10MEN1 | |
| Hydrogen Peroxide SCHEMBL6662236 | 0.72 | KDM4E (0.93) | KDM4EALDH1A1MAPTHSD17B10MEN1 | |
| SCHEMBL9117696 | 0.72 | MEN1 (0.50) | KDM4EALDH1A1MAPTHSD17B10MEN1 | |
| SCHEMBL14208786 | 0.71 | ALDH1A1 (0.59) | KDM4EALDH1A1MAPTHSD17B10MEN1 | |
| SCHEMBL1193507 | 0.71 | ALDH1A1 (0.42) | KDM4EALDH1A1MAPTHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040132676-A1 | Polynucleotide formulation for enhanced intracellular transfer | AVENTIS PASTEUR (FR) | 2004-07-08 | — | — | US | disclosed |
| EP-1363670-A1 | POLYNUCLEOTIDE FORMULATION FOR ENHANCED INTRACELLULAR TRANSFER | Aventis Pasteur (FR) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002067990-A1 | POLYNUCLEOTIDE FORMULATION FOR ENHANCED INTRACELLULAR TRANSFER | AVENTIS PASTEUR (FR) | 2002-09-06 | — | — | WO | disclosed |