Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3666907 | 0.95 | KMT2A (0.52) | TLR7MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL29356683 | 0.93 | KMT2A (0.61) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL15286566 | 0.93 | KMT2A (0.61) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL21950 | 0.93 | KMT2A (0.61) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL3456653 | 0.88 | KMT2A (0.53) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| Thiophene SCHEMBL28276080 | 0.87 | KMT2A (0.55) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL726389 | 0.87 | MEN1 (0.51) | TLR7MEN1KMT2AMAPTSMN1; SMN2 | |
| Benzophenone SCHEMBL28097412 | 0.86 | KMT2A (0.56) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL3457186 | 0.85 | KMT2A (0.49) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 | |
| SCHEMBL3456580 | 0.85 | MEN1 (0.47) | MEN1KMT2AMAPTSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050250947-A1 | Processes for the preparation of 2-aminomethylpyridines and the 2-cyanopyridines used in their preparation | BAYER CROPSCIENCE S.A. | 2005-11-10 | — | — | US | claimed |
| US-6921828-B2 | Processes for the preparation of 2-aminomethlpyridines and the 2-cyanopyridines used in their preparation | BAYER CROPSCIENCE S.A. (FR) | 2005-07-26 | — | — | US | claimed |
| US-20040049048-A1 | Novel process | BAYER CROPSCIENCE LIMITED (GB) | 2004-03-11 | — | — | US | claimed |
| CN-1449383-A | Process for preparing 2-aminoethylpyridines | BAYER CROPSCIENCE SA (FR) | 2003-10-15 | — | — | CN | claimed |
| EP-1311483-A2 | PROCESS FOR THE PREPARATION OF 2-AMINOMETHYLPYRIDINES | Bayer CropScience S.A. (FR) | 2003-05-21 | — | — | EP | claimed |
| EP-1199305-A1 | Process for the preparation of 2-aminomethylpyridines | AVENTIS CROPSCIENCE S.A. (FR) | 2002-04-24 | — | — | EP | claimed |
| WO-2002016322-A2 | PROCESS FOR THE PREPARATION OF 2-AMINOETHYLPYRIDINES | BAYER CROPSCIENCE SA (FR) | 2002-02-28 | — | — | WO | claimed |
| EP-2260704-B1 | Fungicidal compositions comprising a benzamide and cymoxanil | DU PONT (US) | 2013-10-16 | — | — | EP | disclosed |
| EP-1484970-B1 | BENZAMIDES AND COMPOSITIONS COMPRISING BENZAMIDES FOR USE AS FUNGICIDES | DU PONT (US) | 2013-06-26 | — | — | EP | disclosed |
| EP-2260705-A2 | Fungicidal compositions comprising a benzamide and a michondrial respiration inhibitor | E. I. du Pont de Nemours and Company (US) | 2010-12-15 | — | — | EP | disclosed |
| EP-2260703-A2 | Fungicidal compositions comprising a benzamide and fosetyl-aluminium | E. I. du Pont de Nemours and Company (US) | 2010-12-15 | — | — | EP | disclosed |
| EP-2260704-A2 | Fungicidal compositions comprising a benzamide and cymoxanil | E. I. du Pont de Nemours and Company (US) | 2010-12-15 | — | — | EP | disclosed |
| EP-2258190-A2 | Fungicidal compositions comprising a benzamide and a phthalimide | E. I. du Pont de Nemours and Company (US) | 2010-12-08 | — | — | EP | disclosed |
| US-6921828-B2 | Processes for the preparation of 2-aminomethlpyridines and the 2-cyanopyridines used in their preparation | BAYER CROPSCIENCE S.A. (FR) | 2005-07-26 | — | — | US | disclosed |
| EP-1484970-A2 | BENZAMIDES AND COMPOSITIONS COMPRISING BENZAMIDES FOR USE AS FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-12-15 | — | — | EP | disclosed |
| US-20040049048-A1 | Novel process | BAYER CROPSCIENCE LIMITED (GB) | 2004-03-11 | — | — | US | disclosed |
| WO-2003079788-A2 | BENZAMIDES AND COMPOSITIONS BENZAMIDES FOR USE AS FUNGIZIDE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-10-02 | — | — | WO | disclosed |
| EP-1311483-A2 | PROCESS FOR THE PREPARATION OF 2-AMINOMETHYLPYRIDINES | Bayer CropScience S.A. (FR) | 2003-05-21 | — | — | EP | disclosed |
| EP-1199305-A1 | Process for the preparation of 2-aminomethylpyridines | AVENTIS CROPSCIENCE S.A. (FR) | 2002-04-24 | — | — | EP | disclosed |
| WO-2002016322-A2 | PROCESS FOR THE PREPARATION OF 2-AMINOETHYLPYRIDINES | BAYER CROPSCIENCE SA (FR) | 2002-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040049048-A1 | Novel process | UGT1A4, SULT1A1, CYP4A11 | TLR7 3433/4885MEN1 1145/4885KMT2A 2269/4885 |
| US-20050250947-A1 | Processes for the preparation of 2-aminomethylpyridines and the 2-cyanopyridines used in their preparation | QDPR, AASDHPPT, DPYD | TLR7 4191/4885MEN1 1497/4885KMT2A 983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.