Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 3/20 | 0.38 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31141576 | 1.00 | TSHR (0.40) | TSHRNPSR1ACEEDNRAGAA | |
| SCHEMBL4504652 | 0.84 | HDAC4 (0.35) | TSHRNPSR1ACEGAAMAPT | |
| SCHEMBL10732203 | 0.84 | HDAC4 (0.35) | TSHRNPSR1GAAMAPTHDAC4 | |
| SCHEMBL3072198 | 0.84 | ALDH1A1 (0.44) | TSHRNPSR1GAAMAPTHDAC4 | |
| SCHEMBL8180890 | 0.81 | TSHR (0.42) | TSHRNPSR1ACEEDNRAGAA | |
| SCHEMBL6034027 | 0.81 | MAPT (0.43) | TSHRMAPTHDAC4HDAC7HDAC5 | |
| SCHEMBL10824801 | 0.78 | MME (0.40) | TSHRACEGAAMAPTHDAC4 | |
| SCHEMBL10726746 | 0.78 | SSTR4 (0.48) | GAAMAPTHDAC4HDAC7HDAC5 | |
| SCHEMBL10833761 | 0.76 | POLB (0.39) | MAPTHDAC4HDAC7HDAC5CYP2C19 | |
| SCHEMBL8917182 | 0.75 | EDNRA (0.46) | TSHRNPSR1EDNRAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60161905-A | — | — | None | — | — | JP | disclosed |
| US-12421178-B2 | Non-cryogenic, ammonia-free reduction of aryl compounds | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2025-09-23 | — | — | US | disclosed |
| WO-2024210060-A1 | REDUCTION METHOD | 国立大学法人北海道大学 | 2024-10-10 | — | — | WO | disclosed |
| US-20240166664-A1 | TRIHETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | SHANGHAI APEIRON THERAPEUTICS COMPANY LIMITED (CN) | 2024-05-23 | — | — | US | disclosed |
| US-20240092708-A1 | Non-Cryogenic, Ammonia-Free Reduction of Aryl Compounds | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2024-03-21 | — | — | US | disclosed |
| US-11866386-B2 | Non-cryogenic, ammonia-free reduction of aryl compounds | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2024-01-09 | — | — | US | disclosed |
| EP-4289845-A1 | TRIHETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | Shanghai Apeiron Therapeutics Company Limited (CN) | 2023-12-13 | — | — | EP | disclosed |
| US-20220089508-A1 | Non-Cryogenic, Ammonia-Free Reduction of Aryl Compounds | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION | 2022-03-24 | — | — | US | disclosed |
| US-20100168344-A1 | POLYESTER BASED BLEND AND PACKAGING ARTICLE MADE THEREFROM | FAR EASTERN NEW CENTURY CORPORATION (TW) | 2010-07-01 | — | — | US | disclosed |
| EP-1439058-B1 | Planographic printing plate precursor | FUJIFILM CORP (JP) | 2009-12-23 | — | — | EP | disclosed |
| EP-1254895-A1 | NITROGENOUS CYCLIC COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | Eisai Co., Ltd. (JP) | 2002-11-06 | — | — | EP | disclosed |
| US-5328613-A | High temperature polymers formed by melt mixing with finely divided glass and leaching the intercommunicating glass | CORNING INCORPORATED (US) | 1994-07-12 | — | — | US | disclosed |
| EP-0548492-A1 | Polymer membranes for separation processes | Corning Incorporated (US) | 1993-06-30 | — | — | EP | disclosed |
| US-5183607-A | Semipermeable microporous bodies: melt-mixing thermoplastic polymer and leachable glass particles; shaping; leaching without disrupting continuous polymer network | CORNING INCORPORATED | 1993-02-02 | — | — | US | disclosed |
| EP-0363866-A2 | Higher carboxylic acid triester of adamantane triol and lubricating oil containing the same | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1990-04-18 | — | — | EP | disclosed |
| EP-0317348-A1 | Improved lubricant compositions for low-temperature internal combustion engines | EXXON CHEMICAL PATENTS INC. (US) | 1989-05-24 | — | — | EP | disclosed |
| US-4657581-A | AMIDE COMPOUNDS, OF DI OR TETRAHYDRO-1 NAPHTHOIC ACID | SANYO CHEMICAL INDUSTRIES, LTD. (JP) | 1987-04-14 | — | — | US | disclosed |
| JP-S60161905-A | HERBICIDE | SANYO CHEM IND LTD | 1985-08-23 | — | — | JP | disclosed |
| EP-0109815-A1 | Improvements in and relating to substituted tetrahydrona phthalenes | ELI LILLY AND COMPANY (US) | 1984-05-30 | — | — | EP | disclosed |
| US-3968142-A | ANALGESIC, ANTIINFLAMMATORY | CIBA-GEIGY CORPORATION (US) | 1976-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240092708-A1 | Non-Cryogenic, Ammonia-Free Reduction of Aryl Compounds | NAT1, AADAC, ARNT | TSHR 3203/4885NPSR1 3471/4885ACE 976/4885 |
| US-12421178-B2 | Non-cryogenic, ammonia-free reduction of aryl compounds | NAT1, AADAC, ARNT | TSHR 3203/4885NPSR1 3471/4885ACE 976/4885 |
| US-20240166664-A1 | TRIHETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, WEE1, WEE2 | TSHR 3151/4885NPSR1 2569/4885ACE 2272/4885 |
| US-20220089508-A1 | Non-Cryogenic, Ammonia-Free Reduction of Aryl Compounds | NAT1, AADAC, ARNT | TSHR 3203/4885NPSR1 3471/4885ACE 976/4885 |
| US-11866386-B2 | Non-cryogenic, ammonia-free reduction of aryl compounds | NAT1, AADAC, ARNT | TSHR 3203/4885NPSR1 3471/4885ACE 976/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.