SCHEMBL345827

SCHEMBL345827

Cc1c(N)cc(N)cc1Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 9/20 0.50
ALDH1A1 P00352 4/20 0.50
THRB P10828 2/20 0.46
KDM4E B2RXH2 1/20 0.45
MEN1 O00255 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
CD44 P16070 1/20 0.44
TSHR P16473 5/20 0.41
GAA P10253 2/20 0.41
TP53 P04637 1/20 0.39
CASP1 P29466 2/20 0.39
PIK3CA P42336 1/20 0.38
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
HPGD P15428 1/20 0.35
ALOX15 P16050 1/20 0.35
RECQL P46063 1/20 0.35
HSD17B10 Q99714 1/20 0.35
GRIN2D O15399 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1752160 0.86 CYP3A4 (0.58) CYP3A4ALDH1A1THRBKDM4EMEN1
SCHEMBL64498 0.86 TDP1 (0.54) CYP3A4ALDH1A1THRBKDM4EMEN1
Hydrochloric Acid SCHEMBL1483037 0.83 TDP1 (0.52) CYP3A4ALDH1A1THRBKDM4EMEN1
Hydrochloric Acid SCHEMBL10454907 0.83 TDP1 (0.52) CYP3A4ALDH1A1THRBKDM4EMEN1
SCHEMBL29225693 0.81 ALDH1A1 (0.43) CYP3A4ALDH1A1THRBKDM4EMEN1
SCHEMBL8335117 0.79 CYP3A4 (0.46) CYP3A4ALDH1A1KMT2ATDP1CD44
SCHEMBL10947387 0.79 CYP3A4 (0.52) CYP3A4ALDH1A1THRBTDP1CD44
SCHEMBL2963949 0.79 ALDH1A1 (0.46) CYP3A4ALDH1A1THRBKDM4ETDP1
SCHEMBL29434817 0.79 ALDH1A1 (0.46) CYP3A4ALDH1A1THRBKDM4ETDP1
SCHEMBL16728590 0.77 ALDH1A1 (0.44) CYP3A4ALDH1A1MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 523 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114573805-B Preparation method of high-barrier transparent flame-retardant copolymerized nylon 浙江恒逸石化研究院有限公司 2024-03-08 CN claimed
US-11813713-B2 Chemical mechanical polishing pad and polishing method ROHM AND HAAS ELECTRONIC MATERIALS CMP HOLDINGS, INC. (US) 2023-11-14 US claimed
US-11806830-B2 Formulations for chemical mechanical polishing pads and CMP pads made therewith ROHM AND HAAS ELECTRONIC MATERIALS CMP HOLDINGS, INC. (US) 2023-11-07 US claimed
CN-114800255-A Formulation for chemical mechanical polishing pad and CMP pad made therefrom 罗门哈斯电子材料CMP控股股份有限公司 2022-07-29 CN claimed
CN-114770369-A Formulation for chemical mechanical polishing pad with high planarization efficiency and CMP pad made with the same 罗门哈斯电子材料CMP控股股份有限公司 2022-07-22 CN claimed
CN-114770368-A Chemical mechanical polishing pad and polishing method 罗门哈斯电子材料CMP控股股份有限公司 2022-07-22 CN claimed
US-20220226957-A1 CHEMICAL MECHANICAL POLISHING PAD AND POLISHING METHOD U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2022-07-21 US claimed
US-20220226959-A1 FORMULATIONS FOR CHEMICAL MECHANICAL POLISHING PADS AND CMP PADS MADE THEREWITH U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2022-07-21 US claimed
US-20220226958-A1 FORMULATIONS FOR CHEMICAL MECHANICAL POLISHING PADS WITH HIGH PLANARIZATION EFFICIENCY AND CMP PADS MADE THEREWITH U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2022-07-21 US claimed
CN-114573805-A Preparation method of high-barrier transparent flame-retardant copolymerized nylon 浙江恒逸石化研究院有限公司 2022-06-03 CN claimed
EP-0855414-A1 Polyurethane prepolymers for making elastomers having improved dynamic properties AIR PRODUCTS AND CHEMICALS, INC. (US) 1998-07-29 EP claimed
EP-0284803-B1 Novel soluble polymidesiloxanes and methods for their preparation and use OCCIDENTAL CHEM CO (US) 1998-07-15 EP claimed
US-4973645-A BLOCK POLYMERS, OXYDIPHTHALIC ANHYDRIDE, ELECTRONIC APPLICATIONS OCCIDENTAL CHEMICAL CORPORATION (US) 1990-11-27 US claimed
EP-0284803-A2 Novel soluble polymidesiloxanes and methods for their preparation and use Occidental Chemical Corporation (US) 1988-10-05 EP claimed
EP-0283868-A2 Process for producing polyurethane/urea elastomers AIR PRODUCTS AND CHEMICALS, INC. (US) 1988-09-28 EP claimed
US-4722989-A URETHANE-LINKED TOLUENEDIISOCYANATE, DIAMINE CHAIN EXTENSION AIR PRODUCTS AND CHEMICALS, INC. (US) 1988-02-02 US claimed
US-4549007-A REACTION INJECTION MOLDING OF POLYURETHANES-POLYUREAS GAF CORPORATION (US) 1985-10-22 US claimed
US-4523004-A 1,4-BUTANEDIOL AND MONOSUBSTITUTED TOLUENE DIAMINE GAF CORPORATION (US) 1985-06-11 US claimed
US-4507459-A AROMATIC DIAMINE CHAIN EXTENDER, TIRES AIR PRODUCTS AND CHEMICALS, INC. (US) 1985-03-26 US claimed
EP-0102203-A1 Diamine/diol chain extender blends for RIM process GAF CORPORATION (US) 1984-03-07 EP claimed