SCHEMBL1752160

SCHEMBL1752160

Cc1c(Cl)cc(N)cc1Cl

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 7/20 0.58
ALDH1A1 P00352 6/20 0.58
THRB P10828 2/20 0.52
TSHR P16473 4/20 0.47
TP53 P04637 1/20 0.45
CD44 P16070 1/20 0.43
GAA P10253 2/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
GRIN2D O15399 1/20 0.38
GRIN3B O60391 1/20 0.38
GRIN1 Q05586 1/20 0.38
GRIN2A Q12879 1/20 0.38
GRIN2B Q13224 1/20 0.38
GRIN2C Q14957 1/20 0.38
GRIN3A Q8TCU5 1/20 0.38
PIK3CA P42336 1/20 0.36
PLA2G7 Q13093 1/20 0.35
KDM4E B2RXH2 2/20 0.34
MAPT P10636 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10947387 0.86 CYP3A4 (0.52) CYP3A4ALDH1A1THRBTSHRTP53
SCHEMBL345827 0.86 CYP3A4 (0.50) CYP3A4ALDH1A1THRBTSHRTP53
SCHEMBL14872332 0.82 CYP3A4 (0.46) CYP3A4ALDH1A1THRBTSHRTP53
SCHEMBL29739453 0.82 CYP3A4 (0.46) CYP3A4ALDH1A1THRBTSHRTP53
SCHEMBL3786627 0.82 THRB (0.54) CYP3A4ALDH1A1THRBTSHRTP53
SCHEMBL24616492 0.82 CYP3A4 (0.52) CYP3A4ALDH1A1THRBTSHRTP53
SCHEMBL20263523 0.78 CYP3A4 (0.42) CYP3A4ALDH1A1THRBTSHRTP53
SCHEMBL27503497 0.77 ALDH1A1 (0.41) CYP3A4ALDH1A1THRBTSHRTP53
SCHEMBL15277639 0.77 ALDH1A1 (0.41) CYP3A4ALDH1A1THRBTSHRTP53
SCHEMBL27427348 0.75 CYP3A4 (0.39) CYP3A4ALDH1A1THRBTSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 95 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118561708-A Benzoyl bacteria method for synthesizing amine 湖北晟康化工有限公司 2024-08-30 CN claimed
US-12528761-B2 Thyromimetics AUTOBAHN THERAPEUTICS, INC. (US) 2026-01-20 US disclosed
US-20250171462-A1 COMPOUNDS, COMPOSITIONS, AND METHODS TENVIE THERAPEUTICS, INC. 2025-05-29 US disclosed
EP-4486722-A2 COMPOUNDS, COMPOSITIONS, AND METHODS Nico Therapeutics, Inc. (US) 2025-01-08 EP disclosed
CN-119137101-A Compounds, compositions, and methods 尼科治疗有限公司 2024-12-13 CN disclosed
CN-118465140-B Rapid detection method for aromatic nitrogen-containing disinfection byproducts in biological tissues 同济大学 2024-11-05 CN disclosed
CN-118561708-A Benzoyl bacteria method for synthesizing amine 湖北晟康化工有限公司 2024-08-30 CN disclosed
CN-118465140-A Rapid detection method for aromatic nitrogen-containing disinfection byproducts in biological tissues 同济大学 2024-08-09 CN disclosed
WO-2023168298-A2 COMPOUNDS, COMPOSITIONS, AND METHODS DENALI THERAPEUTICS INC. (US) 2023-09-07 WO disclosed
WO-2023168298-A2 COMPOUNDS, COMPOSITIONS, AND METHODS DENALI THERAPEUTICS INC. (US) 2023-09-07 WO disclosed
US-4351959-A Process for preparation of anilines substituted by chlorine in the meta-position RHONE-POULENC AGROCHIMIE (FR) 1982-09-28 US disclosed
US-4340759-A Process for the preparation of anilines substituted by chlorine in the meta-position RHONE-POULENC AGROCHIMIE (FR) 1982-07-20 US disclosed
EP-0051782-A1 Process for the manufacture of m-halogenated anilines BAYER AG (DE) 1982-05-19 EP disclosed
US-4324914-A Process for preparation of anilines substituted by chlorine in the meta-position RHONE-POULENC AGROCHIMIE (FR) 1982-04-13 US disclosed
US-4233055-A Quaternary ammonioalkanecarboxylic acid anilides as plant growth influencing agents CIBA-GEIGY CORPORATION (US) 1980-11-11 US disclosed
US-4193937-A DECHLORINATION OF CHLOROANILINES, SELECTIVE HYDROGENATION CATALYSTS OF NOBLE METAL AND SULFUR BAYER AKTIENGESELLSCHAFT (DE) 1980-03-18 US disclosed
US-4141718-A ANTIGROWTH AGENTS FOR PLANTS CIBA-GEIGY CORPORATION (US) 1979-02-27 US disclosed
US-4139621-A TRANQUILIZERS BEECHAM GROUP LIMITED (GB) 1979-02-13 US disclosed
US-4085141-A Process for the preparation of anilines meta-substituted by chlorine BAYER AKTIENGESELLSCHAFT (DT) 1978-04-18 US disclosed
US-3962336-A Process for the preparation of 5-chloro-2-toluidine HOECHST AKTIENGESELLSCHAFT (DT) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250171462-A1 COMPOUNDS, COMPOSITIONS, AND METHODS SARM1, SARS1, TIAM1 CYP3A4 4262/4885ALDH1A1 4115/4885THRB 1874/4885
US-12528761-B2 Thyromimetics TSHR, THRB, TTR CYP3A4 1632/4885ALDH1A1 1038/4885THRB 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.