Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 5/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3459146 | 0.84 | KMT2A (0.49) | KMT2AMGLLFAAHMAPTHTT | |
| SCHEMBL3458215 | 0.81 | MGLL (0.48) | MGLLFAAHABHD6ALDH1A1 | |
| SCHEMBL2855348 | 0.73 | MGLL (0.71) | MGLLFAAH | |
| SCHEMBL2708024 | 0.69 | KMT2A (0.64) | KMT2AMAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL2856529 | 0.68 | MGLL (0.67) | MGLLFAAH | |
| SCHEMBL2701979 | 0.68 | MGLL (0.61) | MGLLFAAH | |
| SCHEMBL9507549 | 0.67 | MAPK1 (0.64) | KMT2AMAPTHTTNPSR1SMN1; SMN2 | |
| SCHEMBL12171179 | 0.66 | KMT2A (0.52) | KMT2AMAPTHTTSMN1; SMN2LMNA | |
| SCHEMBL9553638 | 0.65 | MGLL (0.60) | MGLLFAAH | |
| SCHEMBL3458598 | 0.65 | MGLL (0.49) | MGLLFAAHABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010151160-A1 | O-SUBSTITUTED 3-N-HETEROARYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL - PORTELA & CA., S.A. (PT) | 2010-12-29 | — | — | WO | claimed |
| WO-2010151160-A1 | O-SUBSTITUTED 3-N-HETEROARYL-1,3,4-OXADIAZOLONES FOR MEDICAL USE | BIAL - PORTELA & CA., S.A. (PT) | 2010-12-29 | — | — | WO | disclosed |