SCHEMBL3458378

SCHEMBL3458378

CCCCc1ccc(N(C=O)c2ccc(CCCC)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
HPGD P15428 2/20 0.47
HSD17B10 Q99714 2/20 0.47
THRA P10827 1/20 0.46
THRB P10828 1/20 0.46
CA2 P00918 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CYP3A4 P08684 2/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C9 P11712 1/20 0.45
CA1 P00915 1/20 0.44
RARB P10826 1/20 0.43
PLK1 P53350 1/20 0.43
ESR1 P03372 2/20 0.41
ADRA2A P08913 2/20 0.41
ADORA3 P0DMS8 2/20 0.41
TACR2 P21452 2/20 0.41
SLC6A2 P23975 2/20 0.41
SLC6A4 P31645 2/20 0.41
SLC6A3 Q01959 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10013045 0.93 ESR1 (0.52) ALDH1A1HSD17B10THRATHRBCYP3A4
SCHEMBL10012647 0.88 ESR1 (0.45) ALDH1A1THRBCA2PLK1ESR1
SCHEMBL5417544 0.84 PLK1 (0.56) THRATHRBRARBPLK1KDM4E
SCHEMBL12882382 0.83 HPGD (0.46) ALDH1A1HPGDHSD17B10THRATHRB
SCHEMBL6688169 0.79 ALDH1A1 (0.40) ALDH1A1HPGDCA2SMN1; SMN2CYP2C9
SCHEMBL10042898 0.79 CA2 (0.59) ALDH1A1HPGDHSD17B10CA2SMN1; SMN2
SCHEMBL3373957 0.78 ALDH1A1 (0.53) ALDH1A1HPGDHSD17B10THRATHRB
SCHEMBL5544979 0.78 ALDH1A1 (0.47) ALDH1A1HSD17B10THRATHRBCA2
Formic Acid SCHEMBL28060935 0.77 ALDH1A1 (0.61) ALDH1A1HPGDHSD17B10THRATHRB
SCHEMBL11887127 0.77 CA2 (0.57) ALDH1A1HPGDHSD17B10CA2SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2478981-B1 SILVER-(CONJUGATED COMPOUND) COMPLEX SUMITOMO CHEMICAL CO (JP) 2020-12-23 EP disclosed
US-9704612-B2 Composition of silver-conjugated compound composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-07-11 US disclosed
US-9412487-B2 Silver-(conjugated compound) composite SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-08-09 US disclosed
US-20140001422-A1 COMPOSITION OF SILVER-CONJUGATED COMPOUND COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2014-01-02 US disclosed
EP-2478981-A1 SILVER-(CONJUGATED COMPOUND) COMPLEX Sumitomo Chemical Co., Ltd (JP) 2012-07-25 EP disclosed
US-20120168693-A1 SILVER-(CONJUGATED COMPOUND) COMPOSITE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-07-05 US disclosed
EP-2169010-A2 Method of producing organic pigment fine-particles, organic pigment fine-particles obtained thereby, liquid dispersion thereof, and composition thereof FUJIFILM Corporation (JP) 2010-03-31 EP disclosed