Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 13/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 8/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15898811 | 0.95 | PDE4B (0.54) | RECQLPDE4BPDE4APDE4CPDE4D | |
| SCHEMBL14629581 | 0.84 | PDE4B (0.41) | RECQLPDE4BHDAC1HDAC2 | |
| SCHEMBL8685698 | 0.84 | CA2 (0.55) | — | |
| SCHEMBL3457950 | 0.82 | MEN1 (0.45) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL3459059 | 0.80 | PDE4B (0.47) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL13034137 | 0.80 | RECQL (0.56) | RECQLPDE4BHDAC1HDAC2PDE4A | |
| SCHEMBL13111720 | 0.80 | RECQL (0.61) | RECQLPDE4BHDAC1HDAC2PDE4A | |
| SCHEMBL14244189 | 0.79 | RECQL (0.60) | RECQLPDE4BHDAC1HDAC2PDE4A | |
| SCHEMBL134754 | 0.79 | RECQL (0.67) | RECQLPDE4BHDAC1HDAC2PDE4A | |
| SCHEMBL13986189 | 0.79 | RECQL (0.60) | RECQLPDE4BHDAC1HDAC2PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |