Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LDHA | P00338 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2617468 | 0.85 | ABCB1 (0.54) | SMN1; SMN2LMNAMAPTKDM4EALDH1A1 | |
| SCHEMBL3457432 | 0.85 | XDH (0.44) | CA2SMN1; SMN2CA1CA9CA12 | |
| SCHEMBL17913604 | 0.85 | CA5A (0.39) | CA2SMN1; SMN2CA1CA9CA12 | |
| SCHEMBL15898811 | 0.84 | PDE4B (0.54) | POLB | |
| SCHEMBL3458432 | 0.84 | RECQL (0.54) | — | |
| SCHEMBL2959929 | 0.83 | CA2 (0.55) | CA2SMN1; SMN2CA1CA9CA12 | |
| SCHEMBL31490068 | 0.83 | CA2 (0.55) | CA2SMN1; SMN2CA1CA9CA12 | |
| SCHEMBL3459059 | 0.83 | PDE4B (0.47) | SMN1; SMN2LMNAMAPT | |
| SCHEMBL17610838 | 0.81 | AR (0.43) | KDM4EALDH1A1 | |
| SCHEMBL27400812 | 0.81 | MRGPRX4 (0.45) | CA2SMN1; SMN2CA1CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024218171-A1 | COMPOUNDS WITH ACTIVITY AGAINST SARS-COV-2 | NATIONAL HELLENIC RESEARCH FOUNDATION (GR) | 2024-10-24 | — | — | WO | disclosed |
| WO-2013049585-A1 | ARYLSUBSTITUTED THIAZOLOTRIAZOLES AND THIAZOLOIMIDAZOLES | HENGRUI (USA), LTD. (US) | 2013-04-04 | — | — | WO | disclosed |
| US-20130085157-A1 | ARYLSUBSTITUTED THIAZOLOTRIAZOLES AND THIAZOLOIMIDAZOLES | SMITH EMILIE D (US) | 2013-04-04 | — | — | US | disclosed |
| CN-101506134-B | Process for producing benzaldehyde compound | UBE INDUSTRIES | 2012-12-05 | — | — | CN | disclosed |
| CN-101506134-A | Process for producing benzaldehyde compound | UBE INDUSTRIES (JP) | 2009-08-12 | — | — | CN | disclosed |
| US-5811439-A | ANTIDIABETIC AGENTS; SIDE EFFECT REDUCTION; ANTILEPEMIC AGENTS | SENGA PHARMACEUTICAL LABORATORY INC. (JP) | 1998-09-22 | — | — | US | disclosed |
| CN-1167111-A | Thiazolidinedione derivatives, method for preparing derivatives and pharmaceutical compositions containing same | SENGA PHARMACEUTICAL LAB INC (JP) | 1997-12-10 | — | — | CN | disclosed |
| EP-0780389-A1 | Thiazolidinedione derivatives, process for their preparation and pharmaceutical compositions containing them | TOBISHI PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130085157-A1 | ARYLSUBSTITUTED THIAZOLOTRIAZOLES AND THIAZOLOIMIDAZOLES | TGM2, CCT5, TSHR | CA2 4362/4885SMN1; SMN2 2309/4885CA1 4835/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.