Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3459059 | 0.94 | PDE4B (0.47) | MEN1KMT2APDE4BPDE4APDE4C | |
| SCHEMBL3458432 | 0.82 | RECQL (0.54) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL8685698 | 0.80 | CA2 (0.55) | CYP19A1HTT | |
| SCHEMBL15898811 | 0.80 | PDE4B (0.54) | PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL13412908 | 0.78 | THRA (0.54) | MEN1KMT2APARP15PARP10EPHX1 | |
| SCHEMBL2617468 | 0.76 | ABCB1 (0.54) | MEN1KMT2AHPGD | |
| SCHEMBL3457432 | 0.76 | XDH (0.44) | MEN1KMT2AHTT | |
| SCHEMBL14629581 | 0.75 | PDE4B (0.41) | MEN1KMT2APDE4BAPOBEC3AHTT | |
| SCHEMBL6943277 | 0.75 | PDE4B (0.45) | MEN1KMT2APARP15PARP10PDE4B | |
| SCHEMBL14084720 | 0.74 | PARP15 (0.58) | MEN1KMT2APARP15PARP10PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010435-A2 | FUSED OXAZOLE AND THIAZOLE DERIVATIVES AS TRPMS MODULATORS | GLENMARK PHARMACEUTICAL S.A. (CH) | 2010-01-28 | — | — | WO | disclosed |