SCHEMBL345853

SCHEMBL345853

C=C(C)C(=O)OCC(O)COc1cc(-n2nc3ccccc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.35
NPC1 O15118 4/20 0.35
RAB9A P51151 4/20 0.35
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 2/20 0.35
HPGD P15428 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
SMN1; SMN2 Q16637 4/20 0.33
POLB P06746 3/20 0.32
NPSR1 Q6W5P4 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
USP2 O75604 1/20 0.32
MDM2 Q00987 1/20 0.32
CYP3A4 P08684 2/20 0.32
CYP2C9 P11712 2/20 0.32
CYP2C19 P33261 2/20 0.32
MAPK1 P28482 1/20 0.32
CYP2D6 P10635 1/20 0.32
LMNA P02545 3/20 0.31
F2R P25116 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9417229 0.92 MAPT (0.33) MAPTNPC1RAB9AALDH1A1KDM4E
SCHEMBL9467298 0.90 CYP1A2 (0.34) MAPTSMN1; SMN2NPSR1USP2LMNA
SCHEMBL19252768 0.86 TDP1 (0.39) MAPTNPC1RAB9AALDH1A1KDM4E
SCHEMBL345854 0.84 NPC1 (0.34) MAPTNPC1RAB9AALDH1A1KDM4E
SCHEMBL5357262 0.84 GAA (0.35) MAPTNPC1RAB9AALDH1A1KDM4E
SCHEMBL9417137 0.84 RAB9A (0.43) MAPTNPC1RAB9AALDH1A1KDM4E
SCHEMBL1855363 0.83 HSP90AB1 (0.34) MAPTTDP1POLBLMNAMEN1
SCHEMBL2777176 0.82 NPC1 (0.41) MAPTNPC1RAB9AALDH1A1KDM4E
SCHEMBL30887176 0.82 MAPK1 (0.38) MAPTNPC1RAB9AALDH1A1KDM4E
SCHEMBL93408 0.79 NPC1 (0.37) MAPTNPC1RAB9AALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2416381-A1 PROTECTIVE SHEET FOR SOLAR CELL MODULE AND SOLAR CELL MODULE LINTEC Corporation (JP) 2012-02-08 EP disclosed
US-20120012164-A1 PROTECTIVE SHEET FOR SOLAR CELL MODULE AND SOLAR CELL MODULE LINTEC CORPORATION (JP) 2012-01-19 US disclosed
US-8003222-B2 Resin composition for forming ultraviolet absorbing layer and laminate comprising ultraviolet absorbing layer NIPPON SHOKUBAI CO., LTD. (JP) 2011-08-23 US disclosed
US-20090110936-A1 Resin Composition for Forming Ultraviolet Absorbing Layer and Laminate Comprising Ultraviolet Absorbing Layer NIPPON SHOKUBAI CO., LTD. (JP) 2009-04-30 US disclosed
WO-2007037501-A9 RESIN COMPOSITION FOR FORMING ULTRAVIOLET ABSORBING LAYER AND LAMINATE COMPRISING ULTRAVIOLET ABSORBING LAYER NIPPON CATALYTIC CHEM IND (JP) 2007-05-24 WO disclosed
EP-0475149-B1 Coating composition and resin article coated thereby NIPPON ARC CO LTD (JP) 1994-11-09 EP disclosed
US-5250359-A Weather resistant, abrasion resistant undercoatings NIPPON ARC CO., LTD. (JP) 1993-10-05 US disclosed