SCHEMBL345854

SCHEMBL345854

CC=CC(=O)OCC(O)COc1cc(-n2nc3ccccc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.34
RAB9A P51151 4/20 0.34
MAPT P10636 4/20 0.34
ALDH1A1 P00352 3/20 0.34
HPGD P15428 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
KDM4E B2RXH2 2/20 0.34
SMN1; SMN2 Q16637 3/20 0.32
NPSR1 Q6W5P4 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
POLB P06746 2/20 0.32
F2R P25116 1/20 0.31
USP2 O75604 1/20 0.30
MDM2 Q00987 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
HTT P42858 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL345853 0.84 MAPT (0.35) NPC1RAB9AMAPTALDH1A1HPGD
SCHEMBL28568918 0.80 EGFR (0.39) NPC1RAB9AALDH1A1KDM4ESMN1; SMN2
SCHEMBL20494988 0.79 ALOX5 (0.30)
SCHEMBL21694047 0.78 ALOX5 (0.39) NPC1RAB9AMAPTALDH1A1HPGD
SCHEMBL20580264 0.78 RAB9A (0.35) NPC1RAB9AMAPTALDH1A1HPGD
SCHEMBL8397405 0.78 KDM4E (0.35) NPC1RAB9AMAPTALDH1A1HPGD
SCHEMBL9417229 0.77 MAPT (0.33) NPC1RAB9AMAPTALDH1A1HPGD
SCHEMBL2778925 0.77 HDAC8 (0.34) NPC1RAB9AMAPTSMN1; SMN2
SCHEMBL10472398 0.77 KDM4E (0.41) NPC1RAB9AMAPTALDH1A1HPGD
SCHEMBL7262236 0.77 ALOX5 (0.40) NPC1RAB9APOLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2416381-A1 PROTECTIVE SHEET FOR SOLAR CELL MODULE AND SOLAR CELL MODULE LINTEC Corporation (JP) 2012-02-08 EP disclosed
US-20120012164-A1 PROTECTIVE SHEET FOR SOLAR CELL MODULE AND SOLAR CELL MODULE LINTEC CORPORATION (JP) 2012-01-19 US disclosed
US-8003222-B2 Resin composition for forming ultraviolet absorbing layer and laminate comprising ultraviolet absorbing layer NIPPON SHOKUBAI CO., LTD. (JP) 2011-08-23 US disclosed
US-20090110936-A1 Resin Composition for Forming Ultraviolet Absorbing Layer and Laminate Comprising Ultraviolet Absorbing Layer NIPPON SHOKUBAI CO., LTD. (JP) 2009-04-30 US disclosed