SCHEMBL3458564

SCHEMBL3458564

Cc1cccc(-c2ccc3c(-c4ccccc4)cccc3n2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
KMT2A Q03164 3/20 0.48
LMNA P02545 3/20 0.48
MEN1 O00255 2/20 0.48
MAPT P10636 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
KDM4E B2RXH2 1/20 0.48
RECQL P46063 1/20 0.48
ACACA Q13085 2/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
NR1I3 Q14994 1/20 0.47
HSP90AA1 P07900 2/20 0.45
THRB P10828 2/20 0.45
GAA P10253 1/20 0.45
TSHR P16473 2/20 0.45
MAPK1 P28482 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5149116 0.98 ALDH1A1 (0.47) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL17453340 0.91 ACACA (0.46) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL12453666 0.87 ACACA (0.60) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL27552816 0.86 TDP1 (0.50) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL13806797 0.85 ACACA (0.47) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL20809054 0.84 BCHE (0.47) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL29262959 0.83 BCHE (0.46) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL31058808 0.83 BCHE (0.46) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL27552828 0.81 ACACA (0.49) ALDH1A1KMT2ALMNAMEN1MAPT
SCHEMBL4438398 0.81 BCHE (0.44) ALDH1A1KMT2ALMNAMEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2267097-B1 Improved electroluminescent stability UNIVERSAL DISPLAY CORP (US) 2018-04-04 EP disclosed
EP-1711579-B1 IMPROVED ELECTROLUMINESCENT STABILITY UNIVERSAL DISPLAY CORP (US) 2016-01-13 EP disclosed
EP-2267097-A1 Improved electroluminescent stability Universal Display Corporation (US) 2010-12-29 EP disclosed
US-7279232-B2 Electroluminescent stability UNIVERSAL DISPLAY CORPORATION (US) 2007-10-09 US disclosed
EP-1711579-A2 IMPROVED ELECTROLUMINESCENT STABILITY Universal Display Corporation (US) 2006-10-18 EP disclosed
WO-2005073339-A2 IMPROVED ELECTROLUMINESCENT STABILITY UNIVERSAL DISPLAY CORPORATION (US) 2005-08-11 WO disclosed
US-20050164030-A1 Electroluminescent stability THE UNIVERSITY OF SOUTHERN CALIFORNIA 2005-07-28 US disclosed