SCHEMBL4438398

SCHEMBL4438398

Cc1cccc(-c2ccc3c(F)cccc3n2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.44
ACHE P22303 1/20 0.44
KMO O15229 1/20 0.44
KMT2A Q03164 3/20 0.43
NPC1 O15118 2/20 0.43
RAB9A P51151 2/20 0.43
NR1I3 Q14994 1/20 0.43
MEN1 O00255 2/20 0.43
ALDH1A1 P00352 3/20 0.42
TSHR P16473 2/20 0.42
MAPK1 P28482 1/20 0.42
THRB P10828 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
IDO1 P14902 1/20 0.41
METAP2 P50579 1/20 0.41
MAPT P10636 2/20 0.40
KDM4E B2RXH2 2/20 0.40
LMNA P02545 2/20 0.40
DHODH Q02127 1/20 0.40
ACP1 P24666 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10078860 0.89 MBNL1 (0.36) KMT2ANPC1RAB9ANR1I3THRB
SCHEMBL13399636 0.85 RAB9A (0.40) BCHEACHEKMOKMT2ANPC1
SCHEMBL20809054 0.84 BCHE (0.47) BCHEACHEKMOKMT2ANPC1
SCHEMBL13658460 0.83 RAB9A (0.50) ACHEKMT2ANPC1RAB9AMEN1
SCHEMBL29262959 0.83 BCHE (0.46) BCHEACHEKMOKMT2ANPC1
SCHEMBL31058808 0.83 BCHE (0.46) BCHEACHEKMOKMT2ANPC1
SCHEMBL20809088 0.81 XDH (0.42) BCHEACHEKMT2ANPC1RAB9A
SCHEMBL3458564 0.81 ALDH1A1 (0.48) BCHEACHEKMOKMT2ANPC1
SCHEMBL5149116 0.80 ALDH1A1 (0.47) BCHEACHEKMOKMT2ANPC1
SCHEMBL13399635 0.79 BCHE (0.42) BCHEACHEKMONPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 55 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11495755-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2022-11-08 US disclosed
EP-3719099-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2022-09-14 EP disclosed
EP-3719099-A1 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2020-10-07 EP disclosed
EP-3719099-A1 PHOSPHORESCENT MATERIALS Universal Display Corporation (US) 2020-10-07 EP disclosed
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-04 US disclosed
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-06-04 US disclosed
EP-3327100-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2020-05-06 EP disclosed
EP-3327100-B1 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORP (US) 2020-05-06 EP disclosed
US-10600975-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-03-24 US disclosed
US-10600975-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2020-03-24 US disclosed
EP-2489716-A2 Phosphorescent materials Universal Display Corporation (US) 2012-08-22 EP disclosed
EP-2489716-A2 Phosphorescent materials Universal Display Corporation (US) 2012-08-22 EP disclosed
EP-2465912-A1 Phosphorescent Materials Universal Display Corporation (US) 2012-06-20 EP disclosed
EP-2465912-A1 Phosphorescent Materials Universal Display Corporation (US) 2012-06-20 EP disclosed
EP-2121871-A2 PHOSPHORESCENT MATERIALS University Display Corporation (US) 2009-11-25 EP disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 US disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 US disclosed
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility UNIVERSAL DISPLAY CORPORATION (US) 2008-10-23 US disclosed
WO-2008109824-A2 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-09-12 WO disclosed
WO-2008109824-A2 PHOSPHORESCENT MATERIALS UNIVERSAL DISPLAY CORPORATION (US) 2008-09-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080261076-A1 Substituted 2-Phenyl quinoline complex with Iridium; high device efficiency, stability, and processibility PCID2, ICMT, ORAI2 BCHE 4176/4885ACHE 1805/4885KMO 886/4885
US-20200176693-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES RUVBL2, TERT, OR10J3 BCHE 3099/4885ACHE 3883/4885KMO 2681/4885
US-11495755-B2 Organic electroluminescent materials and devices RUVBL2, TERT, OR10J3 BCHE 3099/4885ACHE 3883/4885KMO 2681/4885
US-10600975-B2 Organic electroluminescent materials and devices TERT, OR10J3, RUVBL2 BCHE 3427/4885ACHE 3467/4885KMO 2342/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.