Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | PPM1B | O75688 | 2/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL901287 | 0.80 | CTRB1 (0.49) | CTSSCTSKPPM1BCTRB1CA12 | |
| SCHEMBL3459188 | 0.80 | POLB (0.52) | CTSSCTSKPPM1BCTRB1CA12 | |
| SCHEMBL15929820 | 0.73 | CTRB1 (0.50) | CTSSCTSKPPM1BCTRB1CA12 | |
| SCHEMBL15929863 | 0.68 | CPA1 (0.49) | CTRB1 | |
| SCHEMBL18204442 | 0.67 | CTRB1 (0.60) | CTSSCTSKCTRB1LMNAPAM | |
| SCHEMBL15671356 | 0.67 | TRPM8 (0.50) | MEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL1884230 | 0.66 | ATM (0.68) | CTSSCTSKPOLBL3MBTL1LMNA | |
| SCHEMBL9586118 | 0.66 | CTRB1 (0.55) | CTSSCTSKCTRB1LMNAPAM | |
| SCHEMBL1879654 | 0.66 | ATM (0.68) | CTSSCTSKPOLBL3MBTL1LMNA | |
| SCHEMBL803579 | 0.66 | ATM (0.68) | CTSSCTSKPOLBL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010148300-A1 | METHODS OF TREATMENT OF NEUROLOGICAL DISORDERS | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2010-12-23 | — | — | WO | disclosed |