Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTRB1 | P17538 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PPM1B | O75688 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3482668 | 0.84 | TRPM8 (0.55) | CTRB1CTSSCTSKCA12CA1 | |
| SCHEMBL15671356 | 0.83 | TRPM8 (0.50) | MEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL994351 | 0.82 | ACACB (0.42) | CTRB1MEN1KMT2ASCN9A | |
| SCHEMBL1697370 | 0.81 | CTRB1 (0.53) | CTRB1MEN1POLBMAPTAPEX1 | |
| SCHEMBL3459188 | 0.80 | POLB (0.52) | CTRB1MEN1POLBKMT2AL3MBTL1 | |
| SCHEMBL3459035 | 0.80 | CTSS (0.45) | CTRB1MEN1POLBMAPTAPEX1 | |
| SCHEMBL8578236 | 0.79 | EPHX1 (0.50) | MEN1POLBKMT2AL3MBTL1 | |
| SCHEMBL15929820 | 0.78 | CTRB1 (0.50) | CTRB1MEN1POLBMAPTAPEX1 | |
| SCHEMBL1534727 | 0.77 | GPR34 (0.50) | SCN9A | |
| SCHEMBL1695172 | 0.77 | SLC1A3 (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8969620-B2 | Process for the preparation of amino acid derivatives | UCB PHARMA GMBH (DE) | 2015-03-03 | — | — | US | claimed |
| EP-2627639-A1 | N-OPTIONALLY SUBSTITUTED ARYL-2-OLIGOMER-3-ALKOXYPROPIONAMIDES | Nektar Therapeutics (US) | 2013-08-21 | — | — | EP | claimed |
| EP-2621893-A1 | PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES | UCB Pharma GmbH (DE) | 2013-08-07 | — | — | EP | claimed |
| US-20130190533-A1 | PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES | UCB PHARMA GMBH (DE) | 2013-07-25 | — | — | US | claimed |
| WO-2012051551-A1 | N-OPTIONALLY SUBSTITUTED ARYL-2-OLIGOMER-3-ALKOXYPROPIONAMIDES | NEKTAR THERAPEUTICS (US) | 2012-04-19 | — | — | WO | claimed |
| WO-2012041986-A1 | PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES | UCB PHARMA GMBH (DE) | 2012-04-05 | — | — | WO | claimed |
| EP-2352721-A1 | NOVEL PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES | UCB Pharma GmbH (DE) | 2011-08-10 | — | — | EP | claimed |
| WO-2010052011-A1 | NOVEL PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES | UCB PHARMA, S.A. (BE) | 2010-05-14 | — | — | WO | claimed |
| CN-104058991-B | Novel Process For The Preparation Of Amino Acid Derivatives | 优时比制药有限公司 | 2017-04-12 | — | — | CN | disclosed |
| US-8969620-B2 | Process for the preparation of amino acid derivatives | UCB PHARMA GMBH (DE) | 2015-03-03 | — | — | US | disclosed |
| US-8969620-B2 | Process for the preparation of amino acid derivatives | UCB PHARMA GMBH (DE) | 2015-03-03 | — | — | US | disclosed |
| US-8946476-B2 | Process for the preparation of amino acid derivatives | UCB PHARMA GMBH (DE) | 2015-02-03 | — | — | US | disclosed |
| US-8946476-B2 | Process for the preparation of amino acid derivatives | UCB PHARMA GMBH (DE) | 2015-02-03 | — | — | US | disclosed |
| CN-104058991-A | Novel Process For The Preparation Of Amino Acid Derivatives | UCB PHARMA SA | 2014-09-24 | — | — | CN | disclosed |
| US-20100099770-A1 | METHOD FOR TREATING DIABETIC PERIPHERAL NEUROPATHIC PAIN | SCHWARZ PHARMA AG (DE) | 2010-04-22 | — | — | US | disclosed |
| US-20040220077-A1 | Novel use of a peptide class of compound for treating allodynia or other different types of chronic or phantom pain | UCB PHARMA GMBH (DE) | 2004-11-04 | — | — | US | disclosed |
| EP-1383487-A1 | NOVEL USE OF A PEPTIDE CLASS OF COMPOUND FOR TREATING ALLODYNIA OR OTHER DIFFERENT TYPES OF CHRONIC OR PHANTOM PAIN | SCHWARZ PHARMA AG (DE) | 2004-01-28 | — | — | EP | disclosed |
| EP-1243263-B1 | Novel use of a peptide class of compound for treating allodynia or other different types of chronic or phantom pain | SANOL ARZNEI SCHWARZ GMBH (DE) | 2002-11-27 | — | — | EP | disclosed |
| WO-2002074297-A1 | NOVEL USE OF A PEPTIDE CLASS OF COMPOUND FOR TREATING ALLODYNIA OR OTHER DIFFERENT TYPES OF CHRONIC OR PHANTOM PAIN | SCHWARZ PHARMA AG (DE) | 2002-09-26 | — | — | WO | disclosed |
| EP-1243263-A1 | Novel use of a peptide class of compound for treating allodynia or other different types of chronic or phantom pain | SCHWARZ PHARMA AG (DE) | 2002-09-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130190533-A1 | PROCESS FOR THE PREPARATION OF AMINO ACID DERIVATIVES | BCAT2, BCAT1, HNMT | CTRB1 1269/4885MEN1 1539/4885POLB 2119/4885 |
| US-20100099770-A1 | METHOD FOR TREATING DIABETIC PERIPHERAL NEUROPATHIC PAIN | PMP22, GAP43, OPRL1 | CTRB1 4238/4885MEN1 4163/4885POLB 3609/4885 |
| US-20040220077-A1 | Novel use of a peptide class of compound for treating allodynia or other different types of chronic or phantom pain | OPRL1, CALCA, CALCB | CTRB1 3117/4885MEN1 1723/4885POLB 4291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.