Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.56 |
| ▸ | P2RY10 | O00398 | 8/20 | 0.52 |
| ▸ | GPR34 | Q9UPC5 | 3/20 | 0.52 |
| ▸ | DGKA | P23743 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.47 |
| ▸ | GRM8 | O00222 | 1/20 | 0.47 |
| ▸ | GRM6 | O15303 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.47 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.47 |
| ▸ | GSR | P00390 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7083174 | 1.00 | NOD1 (0.56) | NOD1P2RY10GPR34DGKASLC1A3 | |
| SCHEMBL18974248 | 1.00 | NOD1 (0.56) | NOD1P2RY10GPR34DGKASLC1A3 | |
| Hydrochloric Acid SCHEMBL8725898 | 0.98 | NOD1 (0.55) | NOD1P2RY10GPR34DGKASLC1A3 | |
| SCHEMBL30557 | 0.95 | NOD1 (0.62) | NOD1P2RY10GPR34DGKAHTR2C | |
| SCHEMBL17537069 | 0.95 | NOD1 (0.62) | NOD1P2RY10GPR34DGKAHTR2C | |
| SCHEMBL4414480 | 0.94 | NOD1 (0.52) | NOD1P2RY10GPR34DGKADDAH1 | |
| SCHEMBL17537068 | 0.93 | NOD1 (0.64) | NOD1P2RY10GPR34DGKAHTR2C | |
| SCHEMBL17010720 | 0.93 | NOD1 (0.64) | NOD1P2RY10GPR34DGKAHTR2C | |
| SCHEMBL17537066 | 0.93 | NOD1 (0.64) | NOD1P2RY10GPR34DGKAHTR2C | |
| SCHEMBL7351258 | 0.93 | NOD1 (0.64) | NOD1P2RY10GPR34DGKAHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3936469-A | Process for preparing N-carboxylic anhydrides of amino acids | KYOWA HAKKO KOGYO KABUSHIKI KAISHA (JA) | 1976-02-03 | — | — | US | claimed |
| CN-119280225-A | Application of butyl pyroglutamate in preparation of antihypertensive drugs | 江西农业大学 | 2025-01-10 | — | — | CN | disclosed |
| US-20240016946-A1 | DRUG-LOADED MACROMOLECULE AND PREPARATION METHOD THEREFOR | SHANGHAI SHENGDI PHARMACEUTICAL CO., LTD. (CN) | 2024-01-18 | — | — | US | disclosed |
| CN-108218739-B | Butyrylglutamic acid derivative, and composition and application thereof | 广州英赛特生物技术有限公司 | 2020-05-01 | — | — | CN | disclosed |
| EP-2013619-B1 | METHODS FOR USING HUMAN EMBRYONIC STEM CELLS TO EVALUATE TOXICITY OF PHARMACEUTICAL COMPOUNDS & OTHER CHEMICALS | WISCONSIN ALUMNI RES FOUND (US) | 2017-10-11 | — | — | EP | disclosed |
| CN-106518702-A | Aspergillomarasimine A and derivative, synthetic method and application thereof | 北京大学 | 2017-03-22 | — | — | CN | disclosed |
| US-9107931-B2 | Class of cationic lipids for transporting active agents into cells | OZ BIOSCIENCES (FR) | 2015-08-18 | — | — | US | disclosed |
| US-20140255969-A1 | REAGENTS AND METHODS FOR USING HUMAN EMBRYONIC STEM CELLS TO EVALUATE TOXICITY OF PHARMACEUTICAL COMPOUNDS AND OTHER CHEMICALS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-09-11 | — | — | US | disclosed |
| US-8703483-B2 | Reagents and methods for using human embryonic stem cells to evaluate toxicity of pharmaceutical compounds and other chemicals | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-04-22 | — | — | US | disclosed |
| US-20120015865-A1 | NOVEL CLASS OF CATIONIC LIPIDS FOR TRANSPORTING ACTIVE AGENTS INTO CELLS | OZ BIOSCIENCES (FR) | 2012-01-19 | — | — | US | disclosed |
| WO-2006002873-A2 | 1 , 4 -BIS (CARBOXYMETHYL) -6- ' BIS ( CARBOXYMETHYL) AMINO ! -6 -METHYL- PERHYDRO-1 , 4 DIAZEPINE (AAZTA) DERIVATIVES AS LIGANDS IN HIGH RELAXIVITY CONTRAST AGENTS FOR USE IN MAGNETIC RESONANCE IMAGING (MRI ) | BRACCO IMAGING SPA (IT) | 2006-01-12 | — | — | WO | disclosed |
| WO-2005037774-A1 | NOVEL MOLECULES TO DEVELOP DRUG FOR THE TREATMENT OF OSTEOPOROSIS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-04-28 | — | — | WO | disclosed |
| WO-2005037775-A1 | NOVEL MOLECULE FOR INDUCING DIFFERENTIATION OF DENDRITIC CELLS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2005-04-28 | — | — | WO | disclosed |
| CN-1098908-C | Compound film with colour changing according to absorbed moisture quantity and making method thereof | GUANGZHOU INST OF CHEMISTRY (CN) | 2003-01-15 | — | — | CN | disclosed |
| CN-1060504-C | Solid composite colour film and manufacture thereof | GUANGZHOU CHEM INST (CN) | 2001-01-10 | — | — | CN | disclosed |
| CN-1223289-A | Compound film with colour changing according to absorbed moisture quantity and making method thereof | GUANGZHOU INST OF CHEMISTRY (CN) | 1999-07-21 | — | — | CN | disclosed |
| CN-1178328-A | Solid composite colour film and manufacture thereof | GUANGZHOU CHEM INST (CN) | 1998-04-08 | — | — | CN | disclosed |
| EP-0572167-B1 | Cosmetic composition | UNILEVER PLC (GB) | 1996-10-09 | — | — | EP | disclosed |
| EP-0572167-A1 | Cosmestic composition | UNILEVER PLC (GB) | 1993-12-01 | — | — | EP | disclosed |
| CN-1076704-A | Solid composite colour film and method for making with cholester structure | GUANGZHOU CHEM INST (CN) | 1993-09-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240016946-A1 | DRUG-LOADED MACROMOLECULE AND PREPARATION METHOD THEREFOR | MRPL38, MRPS27, MRPS18A | NOD1 1286/4885P2RY10 3609/4885GPR34 2103/4885 |
| US-20120015865-A1 | NOVEL CLASS OF CATIONIC LIPIDS FOR TRANSPORTING ACTIVE AGENTS INTO CELLS | SLC7A1, SLC75A1, SLC47A2 | NOD1 3592/4885P2RY10 2810/4885GPR34 1569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.