SCHEMBL345928

SCHEMBL345928

CCCCCCCCCCCC(=O)OC[C@H](COC(=O)CCC(=O)O)OC(=O)CCCCCCCCCCC

nearest known ligand 0.84

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.84
LMNA P02545 1/20 0.84
PRKCA P17252 4/20 0.72
PRKCE Q02156 2/20 0.72
PRKCQ Q04759 2/20 0.72
PRKCD Q05655 2/20 0.72
LPAR3 Q9UBY5 7/20 0.68
LPAR1 Q92633 4/20 0.68
ENPP2 Q13822 3/20 0.68
SMN1; SMN2 Q16637 1/20 0.68
LPAR2 Q9HBW0 2/20 0.66
MAPT P10636 1/20 0.58
MAPK1 P28482 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13997507 1.00 ALDH1A1 (0.84) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL11782897 1.00 ALDH1A1 (0.84) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL4862128 1.00 ALDH1A1 (0.84) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL18010946 1.00 ALDH1A1 (0.84) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL21472154 1.00 ALDH1A1 (0.84) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL25272152 1.00 ALDH1A1 (0.84) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL6014563 1.00 ALDH1A1 (0.84) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL19285724 1.00 ALDH1A1 (0.84) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL21409342 1.00 ALDH1A1 (0.84) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL18613715 1.00 ALDH1A1 (0.84) ALDH1A1LMNAPRKCAPRKCEPRKCQ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2285772-B1 NEW CLASS OF CATIONIC LIPIDS FOR TRANSPORTING ACTIVE AGENTS INTO CELLS OZ BIOSCIENCES SAS (FR) 2022-07-13 EP disclosed
US-9107931-B2 Class of cationic lipids for transporting active agents into cells OZ BIOSCIENCES (FR) 2015-08-18 US disclosed
US-20120015865-A1 NOVEL CLASS OF CATIONIC LIPIDS FOR TRANSPORTING ACTIVE AGENTS INTO CELLS OZ BIOSCIENCES (FR) 2012-01-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120015865-A1 NOVEL CLASS OF CATIONIC LIPIDS FOR TRANSPORTING ACTIVE AGENTS INTO CELLS SLC7A1, SLC75A1, SLC47A2 ALDH1A1 3856/4885LMNA 1659/4885PRKCA 3130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.