SCHEMBL6014563

SCHEMBL6014563

CCCCCCCCCCCCCCCC(=O)OCC(COC(=O)CCC(=O)O)OC(=O)CCCCCCCCCCCCCCC

nearest known ligand 0.84

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.84
LMNA P02545 1/20 0.84
PRKCA P17252 4/20 0.72
PRKCE Q02156 2/20 0.72
PRKCQ Q04759 2/20 0.72
PRKCD Q05655 2/20 0.72
LPAR3 Q9UBY5 7/20 0.68
LPAR1 Q92633 4/20 0.68
ENPP2 Q13822 3/20 0.68
SMN1; SMN2 Q16637 1/20 0.68
LPAR2 Q9HBW0 2/20 0.66
MAPT P10636 1/20 0.58
MAPK1 P28482 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13997507 1.00 ALDH1A1 (0.84) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL11782897 1.00 ALDH1A1 (0.84) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL4862128 1.00 ALDH1A1 (0.84) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL18010946 1.00 ALDH1A1 (0.84) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL345928 1.00 ALDH1A1 (0.84) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL21472154 1.00 ALDH1A1 (0.84) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL25272152 1.00 ALDH1A1 (0.84) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL19285724 1.00 ALDH1A1 (0.84) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL21409342 1.00 ALDH1A1 (0.84) ALDH1A1LMNAPRKCAPRKCEPRKCQ
SCHEMBL18613715 1.00 ALDH1A1 (0.84) ALDH1A1LMNAPRKCAPRKCEPRKCQ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023123986-A1 UTIDELONE LIPOSOME COMPOSITION, AND PREPARATION METHOD THEREFOR AND USE THEREOF 成都华昊中天药业有限公司 2023-07-06 WO claimed
CN-118251497-A Lipid compositions comprising peptide-lipid conjugates 阿克丘勒斯治疗公司 2024-06-25 CN disclosed
CN-118201639-A Peptide-lipid conjugates 阿克丘勒斯治疗公司 2024-06-14 CN disclosed
EP-4333898-A2 PEPTIDE-LIPID CONJUGATES Arcturus Therapeutics, Inc. (US) 2024-03-13 EP disclosed
EP-4334455-A1 LIPID COMPOSITIONS COMPRISING PEPTIDE-LIPID CONJUGATES Arcturus Therapeutics, Inc. (US) 2024-03-13 EP disclosed
US-20220378702-A1 PEPTIDE-LIPID CONJUGATES ARCTURUS THERAPEUTICS, INC. 2022-12-01 US disclosed
US-20220370624-A1 LIPID COMPOSITIONS COMPRISING PEPTIDE-LIPID CONJUGATES ARCTURUS THERAPEUTICS, INC. 2022-11-24 US disclosed
WO-2022235972-A1 LIPID COMPOSITIONS COMPRISING PEPTIDE-LIPID CONJUGATES ARCTURUS THERAPEUTICS, INC. (US) 2022-11-10 WO disclosed
WO-2022235923-A2 PEPTIDE-LIPID CONJUGATES ARCTURUS THERAPEUTICS, INC. (US) 2022-11-10 WO disclosed
CN-110997693-A Tau aggregation inhibitors 阿德克斯公司 2020-04-10 CN disclosed
US-8192753-B2 pH-sensitive cationic lipids, and liposomes and nanocapsules containing the same MARINA BIOTECH, INC. (US) 2012-06-05 US disclosed
US-8193246-B2 Lipids and lipid assemblies comprising transfection enhancer elements MARINA BIOTECH, INC. (US) 2012-06-05 US disclosed
US-20120021042-A1 Efficient Method For Loading Amphoteric Liposomes With Nucleic Acid Active Substances MARINA BIOTECH, INC. 2012-01-26 US disclosed
US-20090220584-A1 Amphoteric Liposome Formulation BIONTECH PROTEIN THERAPEUTICS GMBH (DE) 2009-09-03 US disclosed
US-20080306153-A1 Lipids and lipid assemblies comprising transfection enhancer elements CEQUENT PHARMACEUTICALS, INC. 2008-12-11 US disclosed
US-20080145413-A1 Lipids and lipid assemblies comprising transfection enhancer elements MARINA BIOTECH, INC. 2008-06-19 US disclosed
US-20060002991-A1 Ph-sensitive cationic lipids, and liposomes and nanocapsules containing the same NOVOSOM VERWALTUNGS GMBH (DE) 2006-01-05 US disclosed
US-6274120-B1 STABILITY; CONTRAST AGENT USED IN ULTRASOUND OR MAGNETIC RESONANCE IMAGE OF HUMAN OR ANIMAL BODY PARTS NYCOMED IMAGING AS (NO) 2001-08-14 US disclosed
EP-0744960-A1 IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS NYCOMED IMAGING AS (NO) 1996-12-04 EP disclosed
WO-1995021631-A1 IMPROVEMENTS IN OR RELATING TO CONTRAST AGENTS NYCOMED IMAGING AS (NO) 1995-08-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080145413-A1 Lipids and lipid assemblies comprising transfection enhancer elements HNRNPH3, SREBF2, PHOSPHO1 ALDH1A1 4867/4885LMNA 446/4885PRKCA 4100/4885
US-20060002991-A1 Ph-sensitive cationic lipids, and liposomes and nanocapsules containing the same LPAR5, LIPA, SGMS2 ALDH1A1 4815/4885LMNA 363/4885PRKCA 296/4885
US-20080306153-A1 Lipids and lipid assemblies comprising transfection enhancer elements SREBF1, SREBF2, ELOVL1 ALDH1A1 3614/4885LMNA 513/4885PRKCA 2154/4885
US-20090220584-A1 Amphoteric Liposome Formulation ANXA5, ANXA11, CLPTM1L ALDH1A1 3919/4885LMNA 1233/4885PRKCA 4204/4885
US-20220370624-A1 LIPID COMPOSITIONS COMPRISING PEPTIDE-LIPID CONJUGATES PHOSPHO1, LNPEP, SLC27A1 ALDH1A1 4452/4885LMNA 659/4885PRKCA 3326/4885
US-20120021042-A1 Efficient Method For Loading Amphoteric Liposomes With Nucleic Acid Active Substances LIPA, ANXA7, ANXA1 ALDH1A1 1330/4885LMNA 123/4885PRKCA 3264/4885
US-20220378702-A1 PEPTIDE-LIPID CONJUGATES GLUL, ASNS, SLC7A11 ALDH1A1 2672/4885LMNA 3270/4885PRKCA 2861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.