Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.44 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9227186 | 0.99 | TSHR (0.47) | TSHRPTPN11CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL9226161 | 0.95 | CYP1A2 (0.50) | TSHRPTPN11CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL9221591 | 0.91 | KMT2A (0.44) | CYP1A2CYP19A1CYP2C9CYP2C19PDK2 | |
| SCHEMBL9225560 | 0.85 | PTGS2 (0.49) | TSHRPRMT5WDR77SMN1; SMN2 | |
| SCHEMBL5057431 | 0.85 | TSHR (0.58) | TSHRPTPN11CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL9698531 | 0.85 | TSHR (0.46) | TSHRPTPN11PDK2GPBAR1PLA2G4B | |
| SCHEMBL29207409 | 0.83 | LTA4H (0.56) | TSHRPTPN11CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL7789317 | 0.82 | TSHR (0.44) | TSHRPTPN11CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL9583558 | 0.80 | TSHR (0.52) | TSHRPTPN11CYP1A2CYP19A1CYP2C9 | |
| SCHEMBL10536207 | 0.80 | NR5A1 (0.49) | TSHRPTPN11CYP1A2CYP19A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0413785-B1 | LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS | MERCK PATENT GMBH (DE) | 1995-12-20 | — | — | EP | disclosed |