Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Xylene SCHEMBL3752326 | 0.95 | CYP1A2 (0.70) | CYP1A2CYP2C9ALDH1A1TP53GLA | |
| SCHEMBL335423 | 0.90 | CYP1A2 (0.63) | CYP1A2CYP2C9ALDH1A1LMNAHPGD | |
| SCHEMBL335424 | 0.89 | CYP1A2 (0.61) | CYP1A2CYP2C9ALDH1A1GLAMAPK1 | |
| SCHEMBL9806106 | 0.89 | CYP1A2 (0.61) | CYP1A2CYP2C9ALDH1A1TP53GLA | |
| SCHEMBL9194077 | 0.89 | CYP1A2 (0.61) | CYP1A2CYP2C9ALDH1A1TP53GLA | |
| SCHEMBL10387619 | 0.89 | CYP1A2 (0.61) | CYP1A2CYP2C9ALDH1A1TP53GLA | |
| SCHEMBL31278334 | 0.88 | CYP1A2 (0.59) | CYP1A2CYP2C9ALDH1A1LMNAKMT2A | |
| SCHEMBL9436866 | 0.88 | CYP1A2 (0.59) | CYP1A2CYP2C9ALDH1A1MAPK1HPGD | |
| SCHEMBL335422 | 0.88 | CYP1A2 (0.59) | CYP1A2CYP2C9ALDH1A1LMNAKMT2A | |
| SCHEMBL7799784 | 0.88 | CYP2C9 (0.51) | CYP1A2CYP2C9ALDH1A1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115876931-B | Method for quantitatively detecting inosine in RNA with high sensitivity | 武汉大学 | 2025-01-21 | — | — | CN | claimed |
| US-12195788-B2 | High-throughput and single nucleotide resolution techniques for the determination of RNA post-transcriptional modifications | UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC. (US) | 2025-01-14 | — | — | US | claimed |
| US-12084417-B2 | Synthesis of N,N-dimethyltryptamine-type compounds, methods, and uses | CYBIN UK LTD (GB) | 2024-09-10 | — | — | US | claimed |
| CN-117214114-B | Method for detecting concentration of trimethylamine | 上海国齐检测技术有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-117214114-A | Method for detecting concentration of trimethylamine | 上海国齐检测技术有限公司 | 2023-12-12 | — | — | CN | claimed |
| EP-4271997-A1 | METALLOENZYMES FOR BIOMOLECULAR RECOGNITION OF N-TERMINAL MODIFIED PEPTIDES | Encodia, Inc. (US) | 2023-11-08 | — | — | EP | claimed |
| CN-116764601-A | Amino polycarboxylic acid compound modified magnetic chitosan microsphere adsorbent, and preparation method and application thereof | 武汉轻工大学 | 2023-09-19 | — | — | CN | claimed |
| US-20230250059-A1 | SYNTHESIS OF N,N-DIMETHYLTRYPTAMINE-TYPE COMPOUNDS, METHODS, AND USES | SMALL PHARMA LTD (GB) | 2023-08-10 | — | — | US | claimed |
| CN-116286690-A | Separation and purification method of tryptophan side group oxidase | 湖北万德瑞生命科学技术有限公司 | 2023-06-23 | — | — | CN | claimed |
| US-11643390-B2 | Synthesis of N,N-dimethyltryptamine-type compounds, methods, and uses | SMALL PHARMA LTD (GB) | 2023-05-09 | — | — | US | claimed |
| CN-115876931-A | Method for high-sensitivity quantitative detection of inosine in RNA | 武汉大学 | 2023-03-31 | — | — | CN | claimed |
| US-20220283175-A1 | METALLOENZYMES FOR BIOMOLECULAR RECOGNITION OF N-TERMINAL MODIFIED PEPTIDES | Encodia, Inc. (US) | 2022-09-08 | — | — | US | claimed |
| US-20220267838-A1 | Sensitive and Accurate Genome-wide Profiling of RNA Structure In Vivo | THE PENN STATE RESEARCH FOUNDATION | 2022-08-25 | — | — | US | claimed |
| WO-2022147334-A1 | METALLOENZYMES FOR BIOMOLECULAR RECOGNITION OF N-TERMINAL MODIFIED PEPTIDES | Encodia, Inc. (US) | 2022-07-07 | — | — | WO | claimed |
| CN-114457460-A | Preparation method of chitosan modified alginic acid fiber | 苏州雷池新材料科技有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-108333347-B | Antinuclear antibody target antigen conjugate reagent, preparation method thereof, kit containing antinuclear antibody target antigen conjugate reagent and application of antinuclear antibody target antigen conjugate reagent | 深圳市新产业生物医学工程股份有限公司 | 2020-09-25 | — | — | CN | claimed |
| CN-106892893-B | Method for preparing lactide from lactic acid oligomer | 中国科学院长春应用化学研究所 | 2020-09-25 | — | — | CN | claimed |
| CN-108333358-B | Method for screening immunoaffinity purification eluent | 深圳市新产业生物医学工程股份有限公司 | 2020-05-01 | — | — | CN | claimed |
| US-4275159-A | IMMOBILIZATION | PROJEKTIERUNG CHEMISCHE VERFAHRENSTECHNIK GMBH (DE) | 1981-06-23 | — | — | US | claimed |
| US-4200692-A | Process for the production of xylose by enzymatic hydrolysis of xylan | PROJEKTIERUNG CHEMISCHE VERFAHRENSTECHNIK GMBH (DE) | 1980-04-29 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230250059-A1 | SYNTHESIS OF N,N-DIMETHYLTRYPTAMINE-TYPE COMPOUNDS, METHODS, AND USES | TPH2, TPH1, HTR2C | CYP1A2 171/4885CYP2C9 193/4885ALDH1A1 1873/4885 |
| US-11643390-B2 | Synthesis of N,N-dimethyltryptamine-type compounds, methods, and uses | TPH2, TPH1, HTR2C | CYP1A2 171/4885CYP2C9 193/4885ALDH1A1 1873/4885 |
| US-12084417-B2 | Synthesis of N,N-dimethyltryptamine-type compounds, methods, and uses | TPH2, TPH1, HTR2C | CYP1A2 171/4885CYP2C9 193/4885ALDH1A1 1873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.