Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | MASP2 | O00187 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HPD | P32754 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19175209 | 0.81 | MASP2 (0.51) | MAPTCYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL3453162 | 0.81 | MASP2 (0.51) | MAPTCYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL10665310 | 0.80 | CYP1A2 (0.60) | MAPTCYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL11380309 | 0.79 | KDM4E (0.63) | MAPTMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL5629465 | 0.79 | CYP2C19 (0.55) | MAPTCYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL4502024 | 0.78 | MASP2 (0.57) | MAPTCYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL3451299 | 0.78 | MASP2 (0.51) | MAPTCYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL11757129 | 0.78 | MASP2 (0.51) | MAPTCYP1A2CYP3A4CYP2C19CYP2D6 | |
| SCHEMBL10980033 | 0.78 | MAPT (0.61) | MAPTCYP3A4CYP2C9MASP2F2 | |
| SCHEMBL13124325 | 0.77 | ALDH1A1 (0.51) | MAPTCYP1A2CYP3A4CYP2C19CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7820705-B2 | Compounds and compositions as PPAR modulators | IRM LLC (BM) | 2010-10-26 | — | — | US | claimed |
| US-7820705-B2 | Compounds and compositions as PPAR modulators | IRM LLC (BM) | 2010-10-26 | — | — | US | disclosed |
| EP-1745027-A4 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2009-06-03 | — | — | EP | disclosed |
| US-20080114044-A1 | Compounds And Compositions As Ppar Modulators | EPPLE ROBERT | 2008-05-15 | — | — | US | disclosed |
| EP-1745027-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM, LLC (BM) | 2007-01-24 | — | — | EP | disclosed |
| WO-2005113519-A1 | COMPOUNDS AND COMPOSITIONS AS PPAR MODULATORS | IRM LLC (BM) | 2005-12-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080114044-A1 | Compounds And Compositions As Ppar Modulators | PPARG, PPARA, PPARD | PTGDR2 309/4885MAPT 3464/4885CYP1A2 1383/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.