Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 4/20 | 0.35 |
| ▸ | CYCS | P99999 | 3/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | GCGR | P47871 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3459959 | 0.89 | TOP1 (0.53) | TOP1TERTCYCSENPP2 | |
| SCHEMBL13183881 | 0.81 | TOP1 (0.47) | TOP1TERTCYCSENPP2 | |
| SCHEMBL13183875 | 0.79 | TERT (0.40) | TOP1TERT | |
| SCHEMBL224502 | 0.79 | TERT (0.39) | TOP1TERTCYCSENPP2 | |
| SCHEMBL28296392 | 0.78 | TERT (0.38) | TOP1TERTCYCSENPP2 | |
| Hydrochloric Acid SCHEMBL3459214 | 0.75 | TERT (0.61) | TOP1TERTCYCSENPP2 | |
| SCHEMBL19894167 | 0.72 | TDP1 (0.41) | — | |
| SCHEMBL3459339 | 0.72 | TOP1 (0.34) | TOP1TERTCYCSENPP2 | |
| SCHEMBL245937 | 0.72 | TOP1 (0.78) | TOP1TERTCYCSENPP2 | |
| SCHEMBL29961137 | 0.72 | TOP1 (0.78) | TOP1TERTCYCSENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2230242-B1 | Synthesis of new asymmetrically meso-substituted water-soluble porphyrins acting as cytostatic agents | JOHANNES KEPLER UNI (AT) | 2013-08-14 | — | — | EP | disclosed |
| EP-2230242-A1 | Synthesis of new asymmetrically meso-substituted water-soluble porphyrins acting as cytostatic agents | Johannes Kepler Universität (AT) | 2010-09-22 | — | — | EP | disclosed |