Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.36 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.35 |
| ▸ | ALB | P02768 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 2/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3240144 | 0.83 | ELANE (0.37) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL27723182 | 0.81 | XIAP (0.36) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL21186 | 0.78 | NOTUM (0.43) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL17372497 | 0.77 | PDE3A (0.34) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL20801121 | 0.76 | FGFR1 (0.37) | LMNATHRBMTORMDM2NCOA1 | |
| Methane SCHEMBL27916787 | 0.76 | NOTUM (0.42) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL27819780 | 0.75 | PARP1 (0.43) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL10679054 | 0.75 | LMNA (0.38) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL27740855 | 0.75 | NOTUM (0.41) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL8709450 | 0.73 | ELANE (0.37) | LMNATHRBMTORMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007015257-A2 | A PROCESS FOR THE PREPARATION OF GEMCITABINE USING NOVEL INTERMEDIATES | HETERO DRUGS LIMITED (IN) | 2007-02-08 | — | — | WO | claimed |
| WO-2010029574-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF GEMCITABINE AND ITS INTERMEDIATES USING NOVEL PROTECTING GROUPS AND ION EXCHANGE RESINS | KANNAN VISHWANATH (IN) | 2010-03-18 | — | — | WO | disclosed |
| WO-2007015257-A2 | A PROCESS FOR THE PREPARATION OF GEMCITABINE USING NOVEL INTERMEDIATES | HETERO DRUGS LIMITED (IN) | 2007-02-08 | — | — | WO | disclosed |