Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | XIAP | P98170 | 1/20 | 0.34 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | CACNA1F | O60840 | 2/20 | 0.33 |
| ▸ | ALB | P02768 | 2/20 | 0.33 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.33 |
| ▸ | CACNA1S | Q13698 | 2/20 | 0.33 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27723182 | 0.87 | XIAP (0.36) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL3460189 | 0.83 | LMNA (0.36) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL21186 | 0.80 | NOTUM (0.43) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL17372497 | 0.80 | PDE3A (0.34) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL20801121 | 0.79 | FGFR1 (0.37) | FGFR1LMNATHRBMTORMDM2 | |
| Methane SCHEMBL27916787 | 0.79 | NOTUM (0.42) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL10679054 | 0.78 | LMNA (0.38) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL27819780 | 0.78 | PARP1 (0.43) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL27740855 | 0.77 | NOTUM (0.41) | FGFR1LMNATHRBMTORMDM2 | |
| SCHEMBL22538799 | 0.76 | FGFR1 (0.34) | FGFR1LMNATHRBMTORMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0934330-A1 | BASE-PROTECTED NUCLEOTIDE ANALOGS WITH PROTECTED THIOL GROUPS | Hanna, Michelle M. (US) | 1999-08-11 | — | — | EP | claimed |
| WO-1998003532-A9 | BASE-PROTECTED NUCLEOTIDE ANALOGS WITH PROTECTED THIOL GROUPS | — | 1998-05-28 | — | — | WO | claimed |
| WO-1998003532-A1 | BASE-PROTECTED NUCLEOTIDE ANALOGS WITH PROTECTED THIOL GROUPS | HANNA MICHELLE M (US) | 1998-01-29 | — | — | WO | claimed |
| WO-1994001445-A1 | BASE-PROTECTED NUCLEOTIDE ANALOGS WITH PROTECTED THIOL GROUPS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-01-20 | — | — | WO | claimed |
| EP-3643706-B1 | MODIFIED NUCLEIC ACID MONOMERS AND OLIGONUCLEIC ACID ANALOGUES, WITH HIGH BIOLOGICAL STABILITY AND TARGET GENE SILENCING ACTIVITY, FOR USE IN THERAPY AND DIAGNOSIS OF CANCER AND VIRAL DISEASES | EISAI R&D MAN CO LTD (JP) | 2023-11-15 | — | — | EP | disclosed |
| CN-112480197-B | Method for synthesizing cytosine nucleoside | 新乡拓新药业股份有限公司 | 2022-03-08 | — | — | CN | disclosed |
| US-11208429-B2 | Modified nucleic acid monomer compound and oligonucleic acid analog | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2021-12-28 | — | — | US | disclosed |
| CN-112480197-A | Method for synthesizing cytosine nucleoside | 新乡拓新药业股份有限公司 | 2021-03-12 | — | — | CN | disclosed |
| EP-3643706-A9 | MODIFIED NUCLEIC ACID MONOMER COMPOUND AND OLIGONUCLEIC ACID ANALOG | Eisai R&D Management Co., Ltd. (JP) | 2020-09-23 | — | — | EP | disclosed |
| CN-108409818-B | Method for synthesizing cytosine nucleoside | 新乡拓新药业股份有限公司 | 2020-09-11 | — | — | CN | disclosed |
| US-20200216488-A1 | MODIFIED NUCLEIC ACID MONOMER COMPOUND AND OLIGONUCLEIC ACID ANALOG | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2020-07-09 | — | — | US | disclosed |
| EP-3643706-A1 | MODIFIED NUCLEIC ACID MONOMER COMPOUND AND OLIGONUCLEIC ACID ANALOG | Eisai R&D Management Co., Ltd. (JP) | 2020-04-29 | — | — | EP | disclosed |
| EP-1334111-A2 | PHOSPHINOAMIDITE CARBOXYLATES AND ANALOGS THEREOF IN THE SYNTHESIS OF OLIGONUCLEOTIDES HAVING REDUCED INTERNUCLEOTIDE CHARGE | Dellinger, Douglas J. (US) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002032912-A2 | PHOSPHINOAMIDITE CARBOXYLATES AND ANALOGS THEREOF IN THE SYNTHESIS OF OLIGONUCLEOTIDES HAVING REDUCED INTERNUCLEOTIDE CHARGE | DELLINGER DOUGLAS J (US) | 2002-04-25 | — | — | WO | disclosed |
| EP-0934330-A1 | BASE-PROTECTED NUCLEOTIDE ANALOGS WITH PROTECTED THIOL GROUPS | Hanna, Michelle M. (US) | 1999-08-11 | — | — | EP | disclosed |
| WO-1998003532-A9 | BASE-PROTECTED NUCLEOTIDE ANALOGS WITH PROTECTED THIOL GROUPS | — | 1998-05-28 | — | — | WO | disclosed |
| WO-1998003532-A1 | BASE-PROTECTED NUCLEOTIDE ANALOGS WITH PROTECTED THIOL GROUPS | HANNA MICHELLE M (US) | 1998-01-29 | — | — | WO | disclosed |
| EP-0689460-A1 | CYCLOBUTYL ANTISENSE OLIGONUCLEOTIDES, METHODS OF MAKING AND USE THEREOF | ISIS PHARMACEUTICALS, INC. (US) | 1996-01-03 | — | — | EP | disclosed |
| WO-1994001445-A1 | BASE-PROTECTED NUCLEOTIDE ANALOGS WITH PROTECTED THIOL GROUPS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-01-20 | — | — | WO | disclosed |
| EP-0136693-A2 | Production of cytidine derivatives | Takeda Chemical Industries, Ltd. (JP) | 1985-04-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200216488-A1 | MODIFIED NUCLEIC ACID MONOMER COMPOUND AND OLIGONUCLEIC ACID ANALOG | POLRMT, DERA, PCNA | ELANE 949/4885FGFR1 2050/4885LMNA 573/4885 |
| US-11208429-B2 | Modified nucleic acid monomer compound and oligonucleic acid analog | POLRMT, DERA, PCNA | ELANE 949/4885FGFR1 2050/4885LMNA 573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.